目录号: A14280
BMI-1 抑制剂
PTC-209 HBr 是 [PTC-209](/ptc-209.html) 的溴化氢盐。PTC-209 是一种强效且选择性的 BMI-1 抑制剂,其在 HEK293T 细胞系中的 IC50 为 0.5 μM,并导致癌症起始细胞(CICs)的不可逆减少。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription | PTC-209 HBr is the hydrobromide salt of PTC-209. PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM in HEK293T cell line, and results in irreversible reduction of cancer-initiating cells (CICs). |
||
---|---|---|---|
Targets |
|
产品信息
目录号 | A14280 |
---|---|
分子式 | C17H13Br2N5OS.HBr |
分子量 | 576.1 |
CAS号 | 1217022-63-3 |
SMILES | CC1=C(N2C=CC=NC2=N1)C3=CSC(=N3)NC4=C(C=C(C=C4Br)OC)Br.Br |
其他名称 | PTX209 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
In vitro (25°C) | DMSO | Warmed: 99 mg/mL (171.84 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+35% PEG 300+2% Tween 80+ddH2O | 6 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Preparing Stock Solutions
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.36 mL | 86.79 mL | 173.58 mL |
0.5 mM | 3.47 mL | 17.36 mL | 34.72 mL |
1 mM | 1.74 mL | 8.68 mL | 17.36 mL |
5 mM | 0.35 mL | 1.74 mL | 3.47 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 PTC-209 HBr | PTC-209 HBr 供应商 | PTC-209 HBr 花费 | PTC-209 HBr 生产商 | 订购 PTC-209 HBr | PTC-209 HBr 代理商
| 购买 1217022-63-3 | 1217022-63-3 供应商 | 1217022-63-3 花费 | 1217022-63-3 生产商 | 订购 1217022-63-3 | 1217022-63-3 代理商