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PTC-209 HBr

目录号: A14280
BMI-1 抑制剂
PTC-209 HBr 是 [PTC-209](/ptc-209.html) 的溴化氢盐。PTC-209 是一种强效且选择性的 BMI-1 抑制剂,其在 HEK293T 细胞系中的 IC50 为 0.5 μM,并导致癌症起始细胞(CICs)的不可逆减少。
Grouped product items
规格 价格 库存 数量
2mg
¥315.00
现货
5mg
¥595.00
现货
10mg
¥980.00
现货
25mg
¥2,100.00
现货
50mg
¥4,060.00
现货
100mg
¥5,670.00
现货
10mM * 1mL in DMSO
¥896.00
现货
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生物活性
Discription

PTC-209 HBr is the hydrobromide salt of PTC-209PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM in HEK293T cell line, and results in irreversible reduction of cancer-initiating cells (CICs).

Targets
Target Value
产品信息
目录号 A14280
分子式 C17H13Br2N5OS.HBr
分子量 576.1
CAS号 1217022-63-3
SMILES CC1=C(N2C=CC=NC2=N1)C3=CSC(=N3)NC4=C(C=C(C=C4Br)OC)Br.Br
其他名称 PTX209
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO Warmed: 99 mg/mL (171.84 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+35% PEG 300+2% Tween 80+ddH2O 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.36 mL 86.79 mL 173.58 mL
0.5 mM 3.47 mL 17.36 mL 34.72 mL
1 mM 1.74 mL 8.68 mL 17.36 mL
5 mM 0.35 mL 1.74 mL 3.47 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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