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R406 (Tamatinib)


Syk 抑制剂

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产品目录号: A10770


产品名 目录号 价格 数量
R406 (freebase) 10mg A10770-10
¥ 1,500.00
R406 (freebase) 25mg A10770-25
¥ 2,800.00
R406 (freebase) 50mg A10770-50
¥ 5,000.00
R406 (freebase) 100mg A10770-100
¥ 8,800.00
R406 (freebase) 10mM * 1mL in DMSO A10770-10mM-D
¥ 1,300.00



R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of Fc receptor signaling.

R406 (Tamatinib)




顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A10770
Mechanism of action Inhibitor
分子量 470.5
化学分子式 C22H23FN6O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 841290-80-0
Synonyms R-406
SMILES code CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
化学名称 N4-(2,2-dimethyl-3-oxo-4H-pyrid[1,4]oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine


R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of Fc receptor signaling.
Syk (Cell-free assay)
41 nM


Solubility (25°C) * In vitro DMSO 21 mg/mL (44.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.27 mL 212.54mL
0.5 mM 4.25 mL 21.25 mL 42.51 mL
1 mM 2.13 mL 10.63 mL 21.25 mL
5 mM 0.43 mL 2.13 mL 4.25 mL

*The above data is based on the productmolecular weight 470.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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