R406 (Tamatinib)

目录号: A10770

Syk Inhibitor

R406 (Tamatinib) Chemical Structure

CAS NO. 841290-80-0

R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of Fc receptor signaling.

库存: 现货

规格 价格 数量
10 mg
¥ 1,500.00
25 mg
¥ 2,800.00
50 mg
¥ 5,000.00
100 mg
¥ 8,800.00
10mM * 1mL in DMSO
¥ 1,300.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of Fc receptor signaling.
靶点信息
Syk (Cell-free assay)
41 nM
In vitro (25°C) DMSO 21 mg/mL (44.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.27 mL 212.54 mL
0.5 mM 4.25 mL 21.25 mL 42.51 mL
1 mM 2.13 mL 10.63 mL 21.25 mL
5 mM 0.43 mL 2.13 mL 4.25 mL

*The above data is based on the productmolecular weight 470.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10770
MECHANISM OF ACTION Inhibitor
M. Wt 470.5
Formula C22H23FN6O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 841290-80-0
Synonyms R-406
SMILES CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C

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