R406 besylate

Name: R406 besylate
SKU: A10769
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A10769

Syk 抑制剂

2 篇发表文献

R406 是一种口服可用的脾酪氨酸激酶抑制剂，其 IC50 为 41 nM。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥315.00	现货
5mg	¥560.00	现货
10mg	¥1,015.00	现货
25mg	¥2,275.00	现货
50mg	¥3,430.00	现货
100mg	¥4,970.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of R406 besylate

R406 (Tamatinib)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用R406 besylate发表的2篇文献

Sina Ghasempour, .et al. , J Immunol, 2024, Oct 1;213(7):988-997 PMID: 39140892

Gabriella Leung, .et al. , JCI insight, 2021, Dec 8;6(23):e149376 PMID: 34673575

生物活性

Discription

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.

Targets

Target	Value

产品信息

目录号	A10769
分子式	C22H23FN6O5.C6H6O3S
分子量	628.6
CAS号	841290-81-1
SMILES	CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O
其他名称	R-406
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	92 mg/mL (146.34 mM)
	Water	Insoluble
	In vivo	5%dmso+95%cornoil	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.91 mL	79.54 mL	159.08 mL
0.5 mM	3.18 mL	15.91 mL	31.82 mL
1 mM	1.59 mL	7.95 mL	15.91 mL
5 mM	0.32 mL	1.59 mL	3.18 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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