R406 besylate

目录号: A10769

Syk Inhibitor

R406 besylate Chemical Structure

CAS NO. 841290-81-1

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.

库存: 现货

规格 价格 数量
2 mg
¥ 500.00
5 mg
¥ 1,000.00
10 mg
¥ 1,500.00
50 mg
¥ 5,000.00
10mM * 1mL in DMSO
¥ 3,730.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.
Targets
Flt3 (Cell-free assay) Syk (Cell-free assay)
N/A41 nM
In vitro (25°C) DMSO 126 mg/mL (200.43 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL (12.72 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.91 mL 79.54 mL 159.08 mL
0.5 mM 3.18 mL 15.91 mL 31.82 mL
1 mM 1.59 mL 7.95 mL 15.91 mL
5 mM 0.32 mL 1.59 mL 3.18 mL

*The above data is based on the productmolecular weight 628.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10769
MECHANISM OF ACTION Inhibitor
M. Wt 628.6
Formula C22H23FN6O5.C6H6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 841290-81-1
Synonyms R-406
SMILES CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O

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