R788 (Fostamatinib)

Name: R788 (Fostamatinib)
SKU: A11926
Price: 210 CNY
Rating: 5 (5 reviews)

目录号: A11926

Syk 抑制剂

5 篇发表文献

R788（Fostamatinib）是一种重要的脾酪氨酸激酶（Syk）抑制剂，显示出对抗激酶介导的IgG Fc伽玛受体信号传导的有效性。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥525.00	现货
10mg	¥805.00	现货
25mg	¥1,505.00	现货
50mg	¥2,415.00	现货
100mg	¥3,990.00	现货
500mg	¥8,785.00	现货
*10mM 1mL in DMSO**	¥665.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of R788 (Fostamatinib)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用R788 (Fostamatinib)发表的5篇文献

Liyanage Manosika Buddhini Perera, .et al. , Biol Pharm Bull, 2024, 47(4):750-757 PMID: 38556260

Mahon OR, .et al. , Acta Biomater, 2018, Jan;65:426-435 PMID: 29104084

Emma M. Corr, .et al. , Arthritis Res Ther, 2017, 19: 23 PMID: 28173838

Cunningham CC, .et al. , Osteoarthritis Cartilage, 2016, Dec;24(12):2141-2152 PMID: 27426968

Corr EM, .et al. , Atherosclerosis, 2016, Aug;251:197-205 PMID: 27356299

生物活性

Discription

R788 (Fostamatinib) is an important spleen tyrosine kinase (Syk) inhibitor, showing efficacy against kinase-mediated IgG Fc gamma receptor signaling.

Targets

Target	Value

产品信息

目录号	A11926
分子式	C23H26FN6O9P
分子量	580.5
CAS号	901119-35-5
SMILES	CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C
其他名称	R-788
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	107 mg/mL (184.34 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.23 mL	86.13 mL	172.27 mL
0.5 mM	3.45 mL	17.23 mL	34.45 mL
1 mM	1.72 mL	8.61 mL	17.23 mL
5 mM	0.34 mL	1.72 mL	3.45 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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