R788 (Fostamatinib)

目录号: A11926

Syk 抑制剂

R788 (Fostamatinib) Chemical Structure

CAS NO. 901119-35-5

R788(Fostamatinib)是重要的脾酪氨酸激酶(Syk)抑制剂,显示出对激酶介导的IgG Fcγ受体信号转导的功效。

库存: 现货

规格 价格 数量
2 mg
¥ 600.00
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
25 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 2,330.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

R788(Fostamatinib)是重要的脾酪氨酸激酶(Syk)抑制剂,显示出对激酶介导的IgG Fcγ受体信号转导的功效。
靶点信息
Syk Adenosine A3 receptor Adenosine transporter Monoamine transporter
41 nM81 nM1.84 μM2.74 μM
In vitro (25°C) DMSO 116 mg/mL (199.84 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.23 mL 86.13 mL 172.27 mL
0.5 mM 3.45 mL 17.23 mL 34.45 mL
1 mM 1.72 mL 8.61 mL 17.23 mL
5 mM 0.34 mL 1.72 mL 3.45 mL

*The above data is based on the productmolecular weight 580.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11926
MECHANISM OF ACTION Inhibitor
M. Wt 580.5
Formula C23H26FN6O9P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 901119-35-5
Synonyms R-788
SMILES CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C

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