Regorafenib monohydrate

目录号: A15218

Tyrosine kinase inhibitor

Regorafenib monohydrate Chemical Structure

CAS NO. 1019206-88-2

Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.

库存: 现货

规格 价格 数量
50 mg
¥ 900.00
100 mg
¥ 1,200.00
200 mg
¥ 1,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.97 mL 99.83 mL 199.67 mL
0.5 mM 3.99 mL 19.97 mL 39.93 mL
1 mM 2 mL 9.98 mL 19.97 mL
5 mM 0.4 mL 2 mL 3.99 mL

*The above data is based on the productmolecular weight 500.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15218
MECHANISM OF ACTION Inhibitor
M. Wt 500.83
Formula C21H17ClF4N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1019206-88-2
Synonyms BAY 73-4506 monohydrate
SMILES CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O

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