Sivelestat sodium salt

目录号: A14073

Neutrophil elastase inhibitor

Sivelestat sodium salt Chemical Structure

CAS NO. 150374-95-1

Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.

库存: 现货

规格 价格 数量
10 mg
¥ 700.00
25 mg
¥ 1,400.00
50 mg
¥ 2,400.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.91 mL 109.54 mL 219.09 mL
0.5 mM 4.38 mL 21.91 mL 43.82 mL
1 mM 2.19 mL 10.95 mL 21.91 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 456.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14073
MECHANISM OF ACTION Inhibitor
M. Wt 456.44
Formula C20H21N2NaO7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 150374-95-1
Synonyms ONO-5046
SMILES CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]

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