Sivelestat

目录号: A14184

Neutrophil elastase inhibitor

Sivelestat Chemical Structure

CAS NO. 127373-66-4

Sivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase).

库存: 现货

规格 价格 数量
10 mg
¥ 650.00
25 mg
¥ 1,300.00
50 mg
¥ 2,400.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Sivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase).
靶点信息
neutrophil elastase
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.02 mL 115.09 mL 230.17 mL
0.5 mM 4.6 mL 23.02 mL 46.03 mL
1 mM 2.3 mL 11.51 mL 23.02 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14184
MECHANISM OF ACTION Inhibitor
M. Wt 434.46
Formula C20H22N2O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 127373-66-4
Synonyms Elastase Inhibitor IV
SMILES CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O

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