Stat

Inhibitory Selectivity

Catalog No.	Inhibitor Name	STAT3	STAT5	Other
A10817	S3I-201	*
A12733	Stattic	**
A14249	SH-4-54	****	****
A10244	Cryptotanshinone	**
A10396	Fludarabine
A16220	Nifuroxazide
A13474	Napabucasin
A15363	Cucurbitacin I			JAK2
A15364	SD 1008			JAK2
A15366	ZM 449829			JAK3, EGFR, JAK1, CDK4
A15729	Corylifol A	*
A15885	HO-3867
A10087	Artesunate			EXP1(a membrane glutathione S-transferase)

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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Cucurbitacin I

Catalog No. A15363
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JAK2/STAT3 抑制剂

Cucurbitacin I（Cucumis sativus L.）可以抑制v-Src转化的NIH 3T3细胞中的磷酸酪氨酸Stat3（信号转导和转录激活因子3）水平。了解更多

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SD 1008

Catalog No. A15364
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JAK2/STAT3 抑制剂

SD 1008是JAK2/STAT3信号通路抑制剂，可额外抑制Src。注意到SD 1008可诱导表达组成性活性酪氨酸磷酸化STAT3的细胞系凋亡。了解更多

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STAT3-IN-3

Catalog No. A18479
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STAT3 inhibitor

STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3). 了解更多

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HJC0152

Catalog No. A16806
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STAT3 抑制剂

HJC0152是一种STAT3抑制剂，具有显着改善的水溶性。了解更多

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STAT3-IN-1

Catalog No. A12232
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STAT3 inhibitor

STAT3-IN-1 (compound 7d) is an excellent, selective and orally active STAT3 inhibitor, with IC50 values of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 (compound 7d) induces tumor apoptosis. 了解更多

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C188-9

Catalog No. A16804
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STAT3 抑制剂

C188-9是一种有效的STAT3抑制剂，它以高亲和力（KD = 4.7±0.4 nM）与STAT3结合。C188-9在小鼠中具有良好的耐受性，显示出良好的口服生物利用度，并且集中在肿瘤中。了解更多

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