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Sunitinib Malate


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产品目录号: A10880


产品名 目录号 价格 数量
Sunitinib Malate 50mg A10880-50
¥ 400.00
Sunitinib Malate 100mg A10880-100
¥ 650.00
Sunitinib Malate 200mg A10880-200
¥ 1,000.00
Sunitinib Malate 500mg A10880-500
¥ 2,000.00
Sunitinib Malate 10mM * 1mL in DMSO A10880-10mM-D
¥ 630.00



Sunitinib is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).

Sunitinib Malate




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Sunitinib Malate 发表的文献 (2)
  • Li Li, .et al. Evidence for activated Lck protein tyrosine kinase as the driver of proliferation in acute myeloid leukemia cell, CTV-1, Leukemia Res, 2019, 78:12-20 PMID: 30660961
  • Brittany M. Duggan, .et al. Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia, Sci Rep, 2017, 7: 1578 PMID: 28484277

Chemical Information

目录号 A10880
Mechanism of action
分子量 532.6
化学分子式 C22H27FN4O2.C4H6O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 341031-54-7
Synonyms SU-11248
SMILES code CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O)C.C([C@@H](C(=O)O)O)C(=O)O
化学名称 N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-hydroxybutanedioate


Sunitinib is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Target Value
VEGFR2IC50: 80nM
FGFR1IC50: 2.9μM
EGFRIC50: >20μM


Solubility (25°C) * In vitro DMSO 15 mg/mL (28.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC, pH3.5 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.78 mL 93.88 mL 187.76mL
0.5 mM 3.76 mL 18.78 mL 37.55 mL
1 mM 1.88 mL 9.39 mL 18.78 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 532.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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