Thrombin

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  1. Melagatran

    Catalog No. A19083
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    Thrombin inhibitor
    Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. 了解更多
  2. RWJ-445167

    Catalog No. A12154
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    dual inhibitor of thrombin and factor Xa
    RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. 了解更多
  3. Inogatran

    Catalog No. A13356
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    synthetic thrombin inhibitor
    Inogatran (H-314-27) is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of arterial and venous thrombotic diseases. 了解更多
  4. Odiparcil

    Catalog No. A21584
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    indirect thrombin inhibitor
    Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) . 了解更多
  5. Thrombin Inhibitor 2

    Catalog No. A21814
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    thrombin inhibitor
    Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor, extracted from US8541580B2. Thrombin Inhibitor 2 has antithrombotic activity. 了解更多
  6. BIBR-1048 (Dabigatran etexilate)

    Catalog No. A10139
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    Thrombin 抑制剂
    BIBR-1048 (Dabigatran etexilate)是dabigatran的前体药物,dabigatran是一种有效的、非肽类小分子化合物,可特异地、可逆性地抑制游离的和结合了血凝块的凝血酶。 了解更多
  7. BIBR 953 (Dabigatran, Pradaxa)

    Catalog No. A10138
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    Thrombin 抑制剂
    BIBR 953 (Dabigatran,Pradaxa)是一种高度选择性,可逆且有效的凝血酶抑制剂,可作为前药达比加群酯口服。它在血栓形成的动物模型中显示出抗血栓形成的功效,起效迅速,可预测的药效学反应。 了解更多
  8. Argatroban

    Catalog No. A11774
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    Thrombin 抑制剂
    Argatroban是一种抗凝剂,是一种小分子直接凝血酶抑制剂,Ki值范围为5 nM-39 nM。 了解更多
  9. Bivalirudin

    Catalog No. A15023
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    Reversible thrombin 抑制剂
    Bivalirudin 是合成的20个残基的肽,可逆地抑制凝血酶。 了解更多
  10. Dabigatran etexilate mesylate

    Catalog No. A15057
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    direct thrombin 抑制剂
    Dabigatran etexilate mesylate是达比加群的口服活性前药。达比加群是一种可逆的选择性直接凝血酶抑制剂(DTI),Ki值为4.5 nM。 了解更多
  11. Dabigatran ethyl ester

    Catalog No. A15058
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    thrombin 抑制剂
    Dabigatran ethyl ester是一种新兴的口服抗凝剂,是凝血酶活性的直接抑制剂。 了解更多
  12. Eltrombopag Olamine

    Catalog No. A15078
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    c-mpl (TpoR) receptor 激动剂
    Eltrombopag olamine是一种新型的口服活性血小板生成素受体(c-mpl)激动剂,可刺激血小板生成。 了解更多
  13. Avatrombopag

    Catalog No. A14087
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    Thrombopoietin(TPO) receptor 激动剂
    Avatrombopag是一种新型的口服活性血小板生成素(TPO)受体激动剂。 了解更多
  14. Ximelagatran

    Catalog No. A12509
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    Thrombin 抑制剂
    Ximelagatran是一种抗凝剂,已被广泛研究作为华法林的替代品,它将克服有问题的饮食,药物相互作用以及与华法林治疗相关的监测问题。 了解更多
  15. PPACK

    Catalog No. A16048
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    Thrombin 抑制剂
    PPACK 是一种有效,选择性和不可逆的凝血酶抑制剂,Ki值为0.24 nM。 了解更多
  16. TPO agonist 1

    Catalog No. A16287
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    TPO 激动剂
    TPO agonist 1 可以通过刺激慢性ITP患者的TPO受体来增加血小板的产生。 了解更多

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