Trusted by 10,000+ Scientists since 2006
微信关注
申请试用装

Y-27632 2HCl

促销

ROCK 抑制剂

0 Customer Reviews
产品目录号: A11001

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Y-27632 5mg A11001-5
¥ 600.00
Y-27632 10mg A11001-10
¥ 900.00
Y-27632 25mg A11001-25
¥ 1,800.00
Y-27632 50mg A11001-50
¥ 2,600.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).

Y-27632 2HCl

双击上述图片即可查看完整大小

缩小
放大

更多视图

顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Y-27632 2HCl 发表的文献 (5)
  • Ooi J, .et al. Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects, Cell Rep, 2019, Feb 26;26(9):2494-2508 PMID: 30811996
  • Scott Bell, .et al. Disruption of GRIN2B Impairs Differentiation in Human Neurons, Stem Cell Reports, 2018, Jul 10; 11(1):183-196 PMID: 29937144
  • Christina Zarouchlioti, .et al. Antisense Therapy for a Common Corneal Dystrophy Ameliorates TCF4 Repeat Expansion-Mediated Toxicity, Am J Hum Genet, 2018, Apr 5; 102(4): 528每539 PMID: 29526280
  • Ai Takemoto, .et al. A critical role of platelet TGF-汕 release in podoplanin-mediated tumour invasion and metastasis, Sci Rep, 2017, 7: 42186 PMID: 28176852
  • Scott Bell, .et al. A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing, Stem Cells Transl Med, 2017, Mar; 6(3): 886每896 PMID: 28170165

Chemical Information

目录号 A11001
Mechanism of action Inhibitor
分子量 320.3
化学分子式 C14H21N3O.2HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 146986-50-7, 129830-38-2
Synonyms N/A
SMILES code C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
化学名称 trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride

生物活性

Description
Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).
Targets
ROCK1 (p160ROCK) (Cell-free assay) ROCK2 (Cell-free assay)
140 nM(Ki)300 nM(Ki)

溶解性

Solubility (25°C) * In vitro DMSO 64 mg/mL warmed (199.83 mM)
Water 14 mg/mL (43.71 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.22 mL 156.1 mL 312.21mL
0.5 mM 6.24 mL 31.22 mL 62.44 mL
1 mM 3.12 mL 15.61 mL 31.22 mL
5 mM 0.62 mL 3.12 mL 6.24 mL

*The above data is based on the productmolecular weight 320.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。


Keywords:购买 Y-27632 2HCl | Y-27632 2HCl 供应商 | 订购 Y-27632 2HCl | Y-27632 2HCl 价格 | Y-27632 2HCl 生产商 | 订单 Y-27632 2HCl | Y-27632 2HCl 代理商 | 购买 146986-50-7, 129830-38-2| 146986-50-7, 129830-38-2 供应商 | 订购 146986-50-7, 129830-38-2 | 146986-50-7, 129830-38-2 价格 | 146986-50-7, 129830-38-2 生产商 | 订单 146986-50-7, 129830-38-2 | 146986-50-7, 129830-38-2 代理商|buy Y-27632 2HCl | Y-27632 2HCl Supplier | purchase Y-27632 2HCl | Y-27632 2HCl cost | Y-27632 2HCl manufacturer | order Y-27632 2HCl | Y-27632 2HCl distributor | buy 146986-50-7, 129830-38-2| 146986-50-7, 129830-38-2 Supplier | purchase 146986-50-7, 129830-38-2 | 146986-50-7, 129830-38-2 cost | 146986-50-7, 129830-38-2 manufacturer | order 146986-50-7, 129830-38-2 | 146986-50-7, 129830-38-2 distributor