Y-27632 2HCl

目录号: A11001

ROCK 抑制剂

Y-27632 2HCl

Y-27632 2HCl Chemical Structure

CAS NO. 146986-50-7, 129830-38-2

Y-27632是一种Rho相关的线圈激酶(ROCK)抑制剂,可提高人类胚胎干细胞(hESCs)的克隆效率。比对其他激酶包括PKC,cAMP依赖性蛋白激酶,MLCK和PAK的作用强200多倍。

库存: 现货

规格 价格 数量
5 mg
¥ 450.00
10 mg
¥ 650.00
25 mg
¥ 1,000.00
50 mg
¥ 1,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Y-27632是一种Rho相关的线圈激酶(ROCK)抑制剂,可提高人类胚胎干细胞(hESCs)的克隆效率。比对其他激酶包括PKC,cAMP依赖性蛋白激酶,MLCK和PAK的作用强200多倍。
靶点信息
ROCK1 (p160ROCK) (Cell-free assay) ROCK2 (Cell-free assay)
140 nM(Ki)300 nM(Ki)
In vitro (25°C) DMSO Warmed: 61 mg/mL (190.46 mM)
Water 13 mg/mL (40.59 mM)
Ethanol Insoluble
In vivo saline 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.22 mL 156.1 mL 312.21 mL
0.5 mM 6.24 mL 31.22 mL 62.44 mL
1 mM 3.12 mL 15.61 mL 31.22 mL
5 mM 0.62 mL 3.12 mL 6.24 mL

*The above data is based on the productmolecular weight 320.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11001
作用机制 Inhibitor (抑制剂)
M. Wt 320.3
Formula C14H21N3O.2HCl
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 146986-50-7, 129830-38-2
SMILES C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

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