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Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.43 mL | 202.15 mL | 404.3 mL |
| 0.5 mM | 8.09 mL | 40.43 mL | 80.86 mL |
| 1 mM | 4.04 mL | 20.22 mL | 40.43 mL |
| 5 mM | 0.81 mL | 4.04 mL | 8.09 mL |
*The above data is based on the productmolecular weight 247.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21448 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 247.34 |
| Formula | C14H21N3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 146986-50-7 |
| Synonyms | Y27632, Y 27632 |
| SMILES | O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2 |
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