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YM-155 hydrochloride是有效的survivin抑制剂，可抑制Survivin启动子活性，IC50为0.54 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.07 mL | 125.36 mL | 250.73 mL |
| 0.5 mM | 5.01 mL | 25.07 mL | 50.15 mL |
| 1 mM | 2.51 mL | 12.54 mL | 25.07 mL |
| 5 mM | 0.5 mL | 2.51 mL | 5.01 mL |
*The above data is based on the productmolecular weight 398.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15284 |
|---|---|
| M. Wt | 398.84 |
| Formula | C20H19ClN4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 355406-09-6 |
| Synonyms | YM155 hydrochloride, YM 155 hydrochloride |
| SMILES | CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Cl-] |
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