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Caspase-3 抑制剂

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产品目录号: A13503


产品名 目录号 价格 数量
Z-DEVD-FMK 2mg A13503-2
¥ 800.00
Z-DEVD-FMK 5mg A13503-5
¥ 1,450.00
Z-DEVD-FMK 25mg A13503-25
¥ 4,000.00
Z-DEVD-FMK 10mM * 1mL in DMSO A13503-10mM-D
¥ 2,100.00



Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Z-DEVD-FMK 发表的文献 (3)
  • Yosefzon Y, .et al. Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size, Mol Cell, 2018, May 17;70(4):573-587.e4 PMID: 29775577
  • Akashi E, .et al. Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells, Oncol Rep, 2017, Jul;38(1):506-514 PMID: 28586026
  • Wenquan Liang, .et al. Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species, Sci Rep, 2016, 6: 38267 PMID: 27905569

Chemical Information

目录号 A13503
Mechanism of action Inhibitor
分子量 668.66
化学分子式 C30H41FN4O12
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 210344-95-9
Synonyms Caspase-3 Inhibitor
SMILES code CC(C)[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H]( CC(=O)OC)NC(=O)OCC1=CC=CC=C1
化学名称 L-?Valinamide, N-?[(phenylmethoxy)?carbonyl]?-?L-???-?aspartyl-?L-???-?glutamyl-?N-?[(1S)?-?3-?fluoro-?1-?(2-?methoxy-?2-?oxoethyl)?-?2-?oxopropyl]?-?, 1,?2-?dimethyl ester


Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.


Solubility (25°C)* In vitro DMSO 100 mg/mL (149.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.96 mL 74.78 mL 149.55mL
0.5 mM 2.99 mL 14.96 mL 29.91 mL
1 mM 1.5 mL 7.48 mL 14.96 mL
5 mM 0.3 mL 1.5 mL 2.99 mL

*The above data is based on the productmolecular weight 668.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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