Z-VAD-FMK

目录号: A12373

Pan Caspase 抑制剂

Z-VAD-FMK

Z-VAD-FMK Chemical Structure

CAS NO. 187389-52-2

Z-VAD-FMK是一种细胞可渗透、不可逆的泛胱天蛋白酶抑制剂。体外抑制肿瘤细胞caspase加工和凋亡诱导(IC50 = 0.0015 - 5.8 mM)。活跃在体内。

库存: 现货

规格 价格 数量
1 mg
¥ 400.00
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
25 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 2,460.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Z-VAD-FMK是一种细胞可渗透、不可逆的泛胱天蛋白酶抑制剂。体外抑制肿瘤细胞caspase加工和凋亡诱导(IC50 = 0.0015 - 5.8 mM)。活跃在体内。
靶点信息
Pan-caspase (THP.1, Jurkat T-cells)
0.0015 - 5.8 mM (IC50)
In vitro (25°C) DMSO 80 mg/mL (171.12 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+35 %PEG 300+2%Tween 80+ddH2O 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.39 mL 106.95 mL 213.91 mL
0.5 mM 4.28 mL 21.39 mL 42.78 mL
1 mM 2.14 mL 10.7 mL 21.39 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12373
作用机制 Inhibitor (抑制剂)
M. Wt 467.49
Formula C22H30FN3O7
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 187389-52-2
SMILES C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1

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