Z-VAD-FMK

目录号: A12373

Pan Caspase Inhibitor

Z-VAD-FMK

Z-VAD-FMK Chemical Structure

CAS NO. 187389-52-2

Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 - 5.8 mM). Active in vivo.

库存: 现货

规格 价格 数量
1 mg
¥ 400.00
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
25 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 2,460.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 - 5.8 mM). Active in vivo.
Targets
Pan-caspase (THP.1, Jurkat T-cells)
0.0015 - 5.8 mM (IC50)
In vitro (25°C) DMSO 93 mg/mL (198 mM)
Water <1 mg/mL (<1 mM)
Ethanol 24 mg/mL heating (51 mM)
In vivo DMF 84 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.39 mL 106.95 mL 213.91 mL
0.5 mM 4.28 mL 21.39 mL 42.78 mL
1 mM 2.14 mL 10.7 mL 21.39 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12373
MECHANISM OF ACTION Inhibitor
M. Wt 467.49
Formula C22H30FN3O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 187389-52-2
Synonyms N/A
SMILES C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1

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