ACLY

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  1. BMS303141

    Catalog No. A13807
    ATP-citrate lyase inhibitor
    BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model. 了解更多
  2. ETC-1002

    Catalog No. A15815
    ACL inhibitor and AMPK activator
    ETC-1002 is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule; activator of hepatic AMP-activated protein kinase (AMPK); also has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM). 了解更多

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