BIBW2992 (Afatinib)

目录号: A10141

EGFR inhibitor

BIBW2992 (Afatinib) Chemical Structure

CAS NO. 439081-18-2

BIBW2992 (Afatinib) is tyrosine kinase inhibitor (TKI) that irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 500.00
25 mg
¥ 700.00
100 mg
¥ 1,900.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

BIBW2992 (Afatinib) is tyrosine kinase inhibitor (TKI) that irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.
Targets
EGFR (L858R) (Cell-free assay) EGFR (wt) (Cell-free assay) EGFR (L858R/T790M) (Cell-free assay) HER2 (Cell-free assay)
0.4 nM0.5 nM10 nM14 nM
In vitro (25°C) DMSO 97 mg/mL (199.61 mM)
Water <1 mg/mL (<1 mM)
Ethanol 15 mg/mL (30.86 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.58 mL 102.9 mL 205.8 mL
0.5 mM 4.12 mL 20.58 mL 41.16 mL
1 mM 2.06 mL 10.29 mL 20.58 mL
5 mM 0.41 mL 2.06 mL 4.12 mL

*The above data is based on the productmolecular weight 485.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10141
MECHANISM OF ACTION Inhibitor
M. Wt 485.9
Formula C24H25ClFN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 439081-18-2
Synonyms Tomtovok,Afatinib
SMILES CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 BIBW2992 (Afatinib) | BIBW2992 (Afatinib) 供应商 | 订购 BIBW2992 (Afatinib) | BIBW2992 (Afatinib) 价格 | BIBW2992 (Afatinib) 生产商 | 订单 BIBW2992 (Afatinib) | BIBW2992 (Afatinib) 代理商 | 购买 439081-18-2| 439081-18-2 供应商 | 订购 439081-18-2 | 439081-18-2 价格 | 439081-18-2 生产商 | 订单 439081-18-2 | 439081-18-2 代理商|buy BIBW2992 (Afatinib) | BIBW2992 (Afatinib) Supplier | purchase BIBW2992 (Afatinib) | BIBW2992 (Afatinib) cost | BIBW2992 (Afatinib) manufacturer | order BIBW2992 (Afatinib) | BIBW2992 (Afatinib) distributor | buy 439081-18-2| 439081-18-2 Supplier | purchase 439081-18-2 | 439081-18-2 cost | 439081-18-2 manufacturer | order 439081-18-2 | 439081-18-2 distributor
Rewards