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Crizotinib hydrochloride

c-Met/NPM-ALK 抑制剂

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产品目录号: A16245

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Crizotinib hydrochloride 10mg A16245-10
¥ 400.00
Crizotinib hydrochloride 50mg A16245-50
¥ 1,600.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK.

Crizotinib hydrochloride

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Crizotinib hydrochloride 发表的文献 (1)
  • Brittany M. Duggan, .et al. Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia, Sci Rep, 2017, 7: 1578 PMID: 28484277

Chemical Information

目录号 A16245
Mechanism of action Inhibitor
分子量 486.8
化学分子式 C21H23Cl3FN5O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1415560-69-8
Synonyms PF-02341066 hydrochloride, PF 02341066 hydrochloride
SMILES code C[C@](OC(C=C(C(C=N1)=CN1C2CCNCC2)C=N3)=C3N)([H])C4=C(Cl)C=CC(F)=C4Cl.Cl
化学名称 (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine hydrochloride

生物活性

Description
Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.54 mL 102.71 mL 205.42mL
0.5 mM 4.11 mL 20.54 mL 41.08 mL
1 mM 2.05 mL 10.27 mL 20.54 mL
5 mM 0.41 mL 2.05 mL 4.11 mL

*The above data is based on the productmolecular weight 486.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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