PF-2341066 (Crizotinib)

Name: PF-2341066 (Crizotinib)
SKU: A10712
Price: 175 CNY
Rating: 5 (7 reviews)

目录号: A10712

ALK/ c-Met 抑制剂

7 篇发表文献

PF-2341066（克唑替尼）是一种c-Met激酶和NPM-ALK的抑制剂。PF-2341066在ALK阳性ALCL细胞中抑制细胞增殖（IC50=30纳摩尔）。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥280.00	现货
25mg	¥350.00	现货
50mg	¥385.00	现货
100mg	¥560.00	现货
200mg	¥630.00	现货
500mg	¥1,050.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of PF-2341066 (Crizotinib)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PF-2341066 (Crizotinib)发表的7篇文献

Sang-Yun Lee, .et al. , J Exp Clin Cancer Res, 2023, Nov 22;42(1):309 PMID: 37993887

Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Yu B, .et al. , J Sep Sci, 2020, Jan 22 PMID: 31970927

Li Li, .et al. , Leukemia Res, 2019, 78:12-20 PMID: 30660961

Li T, .et al. , Oncogene, 2018, Nov;37(47):6180-6194 PMID: 30013190

Saki Omote, .et al. , Sci Rep, 2018, 8: 9237 PMID: 29915248

Arakawa H, .et al. , J Pharm Sci, 2017, Sep;106(9):2899-2903 PMID: 28336299

生物活性

Discription

PF-2341066 (Crizotinib) is an inhibitor of the c-Met kinase and the NPM-ALK. PF-2341066 inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM).

Targets

Target	Value

产品信息

目录号	A10712
分子式	C21H22Cl2FN5O
分子量	450.3
CAS号	877399-52-5
SMILES	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	8 mg/mL (17.76 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+dd H2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.21 mL	111.04 mL	222.07 mL
0.5 mM	4.44 mL	22.21 mL	44.41 mL
1 mM	2.22 mL	11.1 mL	22.21 mL
5 mM	0.44 mL	2.22 mL	4.44 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 PF-2341066 (Crizotinib) | PF-2341066 (Crizotinib) 供应商 | PF-2341066 (Crizotinib) 花费 | PF-2341066 (Crizotinib) 生产商 | 订购 PF-2341066 (Crizotinib) | PF-2341066 (Crizotinib) 代理商 | 购买 877399-52-5 | 877399-52-5 供应商 | 877399-52-5 花费 | 877399-52-5 生产商 | 订购 877399-52-5 | 877399-52-5 代理商