MK-2206 2HCl

目录号: A10003

AKT Inhibitor

MK-2206 2HCl

MK-2206 2HCl Chemical Structure

CAS NO. 1032350-13-2

MK-2206 2HCl是Akt1 / 2/3的高选择性抑制剂,IC50分别为8 nM / 12 nM / 65 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
25 mg
¥ 1,500.00
50 mg
¥ 2,500.00
10mM * 1mL in DMSO
¥ 1,170.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

MK-2206 2HCl是Akt1 / 2/3的高选择性抑制剂,IC50分别为8 nM / 12 nM / 65 nM。
Targets
Akt1 (Cell-free assay) Akt2 (Cell-free assay) Akt3 (Cell-free assay)
8 nM12 nM65 nM
In vitro (25°C) DMSO 14 mg/mL (29.14 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 17 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.82 mL 104.08 mL 208.16 mL
0.5 mM 4.16 mL 20.82 mL 41.63 mL
1 mM 2.08 mL 10.41 mL 20.82 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10003
MECHANISM OF ACTION Inhibitor
M. Wt 480.4
Formula C25H21N5O.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1032350-13-2
Synonyms MK2206
SMILES C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl

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