Opioid Receptors

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  1. AR-M 1000390 hydrochloride

    Catalog No. A21911
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    δ opioid receptor agonist
    AR-M 1000390 hydrochloride is an exceptionally selective, potent δ opioid receptor agonist with an EC50 of 7.2??0.9 nM for δ agonist potency. 了解更多
  2. GSK1521498 free base (hydrochloride)

    Catalog No. A21792
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    μ-opioid receptor (MOR) antagonist
    GSK1521498 free base (hydrochloride) is a potent and selective μ-opioid receptor (MOR) antagonist. 了解更多
  3. CYT-1010 hydrochloride

    Catalog No. A21348
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    mu-opioid receptor agonist
    CYT-1010 hydrochloride is a mu-opioid receptor agonist extracted from patent WO2013173730A2, with EC50s of 13.1 nM and 0.0053 nM on beta-arrestin recruitment and inhibition of cAMP production, respectively. 了解更多
  4. JDTic

    Catalog No. A11468
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    κ-opioid receptor antagonist
    JDTic is a highly selective antagonist for the κ-opioid receptor; without affecting the μ- or δ-opioid receptors. 了解更多
  5. DPI-3290

    Catalog No. A13699
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    opioid receptors agonist
    DPI-3290 (Org 41793) is a potent and specific opioid receptors agonist with Ki values of 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively. 了解更多
  6. GSK1521498 free base

    Catalog No. A18994
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    μ-opioid receptor antagonist
    GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs. 了解更多
  7. LY2795050

    Catalog No. A15149
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    k-opioid receptor 拮抗剂
    LY2795050是新型选择性κ阿片受体(KOR)拮抗剂(IC50 = 0.72 nM),具有作为PET示踪剂在体内对KOR成像的潜力。 了解更多
  8. Methylnaltrexone Bromide

    Catalog No. A15159
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    μ-opioid 拮抗剂
    Methylnaltrexone Bromide是一种作用于胃肠道以减少阿片类药物引起的便秘的具有信息素作用的?-opioid拮抗剂。 了解更多
  9. BTRX-335140

    Catalog No. A18583
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    κ opioid receptor antagonist
    BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. 了解更多
  10. Trimebutine maleate

    Catalog No. A18115
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    ?- opioid receptor agonist
    Trimebutine Maleate is a drug with antimuscarinic and weak mu opioid agonist effects. Trimebutine Maleate modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome. 了解更多
  11. Bevenopran

    Catalog No. A17110
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    opioid receptor antagonis
    Bevenopran,也称为CB-5945,ADL-5945,MK-2402,OpRA III,是一种外周选择性μ-和δ-阿片样物质受体拮抗剂。 了解更多
  12. Cebranopadol (GRT-6005)

    Catalog No. A12670
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    Opioid Receptor 激动剂
    Cebranopadol是一种有效的伤害感受器/孤儿蛋白FQ肽(NOP)和阿片受体激动剂。作用于人NOP,MOP,KOP 和δ-阿片肽(DOP)受体,Ki/EC50 分别为 0.9 nM/13 nM,0.7 nM/1.2 nM,2.6 nM/17 nM,18 nM/110 nM。 了解更多
  13. Docusate Sodium

    Catalog No. A16155
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    Docusate Sodium是一种用于治疗便秘的泻药,对于便秘,由于使用了鸦片制剂,可能与刺激性泻药一起使用,可以通过口腔或直肠服用。 了解更多
  14. Naloxegol Oxalate

    Catalog No. A15972
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    Opioid 拮抗剂
    Naloxegol Oxalate是用于治疗阿片类药物引起的便秘的外周选择性阿片类药物拮抗剂。 了解更多
  15. Alvimopan monohydrate

    Catalog No. A14992
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    ?-opioid receptor 激动剂
    Alvimopan monohydrate是一种外围作用的类阿片受体(PAM-OR,IC50 = 1.7 nM)拮抗剂,可促进术后肠胃的恢复。 了解更多
  16. Alvimopan dihydrate

    Catalog No. A14991
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    ?-opioid receptor 激动剂
    Alvimopan dihydrate (LY 246736,ADL 8-2698)是一种外周作用的类阿片受体(PAM-OR,IC50 = 1.7 nM)拮抗剂,可促进术后胃肠道恢复。 了解更多
  17. ADL5747

    Catalog No. A13479
    δ opioid receptor 激动剂
    ADL5747是一种选择性的非肽类δ opioid激动剂。 了解更多
  18. U-69593

    Catalog No. A14187
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    κ1-opioid receptor 激动剂
    U-69593是有效的选择性κ1阿片受体激动剂(EC50 = 80-109 nM)。在体内有活性。抗伤害感受。 了解更多
  19. Nalmefene hydrochloride

    Catalog No. A13843
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    dopamine receptor 激动剂
    Nalmefene hydrochloride是opioid receptor拮抗剂。 了解更多
  20. Nalfurafine hydrochloride

    Catalog No. A12579
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    opioid κ-selective 激动剂
    Nalfurafine hydrochloride是一种κ-opioid激动剂。 了解更多
  21. Trimebutine

    Catalog No. A11718
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    Trimebutine是一种具有抗毒蕈碱和弱μ阿片激动剂作用的药物。 了解更多
  22. BAN ORL 24

    Catalog No. A11322
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    NOP 拮抗剂
    BAN ORL 24是一种强效选择性NOP受体拮抗剂。 了解更多
  23. Alvimopan (ADL 8-2698)

    Catalog No. A11292
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    Opioid 拮抗剂
    Alvimopan (ADL 8-2698)表现为外周作用的opioid拮抗剂,Alvimopan竞争性结合胃肠道中的mu-opioid receptor。 了解更多
  24. BRL 52537 HCl

    Catalog No. A11210
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    Opioid Receptors 激动剂
    BRL 52537 hydrochloride是一种高度选择性和有效的κ阿片类激动剂(Ki = 0.24 nM)。比吗啡强25倍。 了解更多
  25. MCOPPB 3HCl

    Catalog No. A10561
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    NOP receptor 激动剂
    MCOPPB 3HCl是一种用作伤害感受器受体的有效和选择性激动剂的化合物,pKi为10.07。 了解更多
  26. JTC-801

    Catalog No. A11076
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    Opioid Receptor 拮抗剂
    JTC-801是nociceptin receptor(也称为ORL-1受体)的选择性拮抗剂。 了解更多
  27. ADL5859 HCl

    Catalog No. A11072
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    Opioid Receptor 激动剂
    ADL5859 HCl是高效的选择性δ阿片受体激动剂,Ki值为0.84 nM,ED50值为20 nM。 了解更多

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