S-Ruxolitinib

目录号: A14955

JAK 抑制剂

S-Ruxolitinib

S-Ruxolitinib Chemical Structure

CAS NO. 941685-37-6

S-Ruxolitinib是INCB018424的手性化合物,是一种有效且选择性的小分子Janus激酶1(JAK1)和JAK2抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 1,300.00
10 mg
¥ 2,000.00
50 mg
¥ 5,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

S-Ruxolitinib是INCB018424的手性化合物,是一种有效且选择性的小分子Janus激酶1(JAK1)和JAK2抑制剂。
Targets
Target Value
JAK2IC50: 2.8nM
JAK1IC50: 3.3nM
TYK2IC50: 19nM
JAK3IC50: 428nM
Chk2IC50: >1μM
c-MetIC50: >10μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.64 mL 163.2 mL 326.4 mL
0.5 mM 6.53 mL 32.64 mL 65.28 mL
1 mM 3.26 mL 16.32 mL 32.64 mL
5 mM 0.65 mL 3.26 mL 6.53 mL

*The above data is based on the productmolecular weight 306.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14955
作用机制 Inhibitor (抑制剂)
M. Wt 306.37
Formula C17H18N6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 941685-37-6
Synonyms INCB018424
SMILES C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3

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