Prostanoid Receptors

28 个项目


  1. Treprostinil sodium

    Catalog No. A21046
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    DP1/EP2 agonist
    Treprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6??0.1 and 6.2??1.2 nM, respectively. 了解更多
  2. CJ-42794

    Catalog No. A21948
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    EP4 antagonist
    CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3). 了解更多
  3. AGN 210676

    Catalog No. A21281
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    prostaglandin EP2 agonist
    AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM. 了解更多
  4. Terutroban

    Catalog No. A20884
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    thromboxane-prostaglandin receptor antagonist
    Terutroban is a thromboxane-prostaglandin receptor antagonist. 了解更多
  5. MK-2894 sodium salt

    Catalog No. A11498
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    EP4 antagonist
    MK-2894 sodium salt is a highly potent and selective second generation EP4 antagonist. 了解更多
  6. (+)-Cloprostenol

    Catalog No. A12979
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    prostaglandin F2α (PGF2α) analogue
    (+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor. 了解更多
  7. ONO-AE3-208

    Catalog No. A11516
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    EP4 antagonist
    ONO-AE3-208 is an EP4 antagonist, and suppresses cell invasion, migration, and metastasis of prostate cancer. 了解更多
  8. CAY10471 Racemate

    Catalog No. A11760
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    Prostaglandin D2 receptor CRTH2 antagonist
    CAY10471 Racemate (TM30089 Racemate) is a potent and highly selective prostaglandin D2 receptor CRTH2 antagonist. 了解更多
  9. Aligeron

    Catalog No. A13241
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    prostaglandin (PG) antagonist
    Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties. 了解更多
  10. GSK726701A

    Catalog No. A20101
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    EP4 partial agonist
    GSK726701A is a novel prostaglandin E2 receptor 4 (EP4) partial agonist with a pEC50 of 7.4. 了解更多
  11. Dinoprost tromethamine

    Catalog No. A17505
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    Prostaglandin Receptor inhibitor
    Dinoprost Tromethamine, also known as Dinoprost Trometamol, is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. 了解更多
  12. Benorylate

    Catalog No. A17501
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    Prostaglandin Receptor inhibitor
    Benorilate, also known as Win-11450, is an ester of aspirin and paracetamol with analgesic, antipyretic, and anti-inflammatory activity used in the treatment of rheumatoid diseases. Benorilate has less severe side effects than aspirin. 了解更多
  13. Tafluprost

    Catalog No. A17442
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    prostaglandin analogue
    Tafluprost, also known as MK2452 and AFP-168, is a prostaglandin analogue used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. 了解更多
  14. GSK-269984A

    Catalog No. A17096
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    EP1 receptor 拮抗剂
    GSK-269984A是新型的EP1受体拮抗剂。pIC50 值为 7.9。 了解更多
  15. Grapiprant (CJ-023423)

    Catalog No. A15964
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    prostaglandin EP4 receptor 拮抗剂
    Grapiprant (CJ-023423)是一种具有抗痛觉过敏特性的新型,有效且选择性的前列腺素EP4受体拮抗剂。 了解更多
  16. TG6-10-1

    Catalog No. A15968
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    Prostaglandin E2 receptor 拮抗剂
    TG6-10-1是前列腺素E2受体亚型EP2的有效和选择性拮抗剂。 了解更多
  17. CP544326 (Taprenepag)

    Catalog No. A15853
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    EP2 激动剂?
    CP544326 (Taprenepag)是一种有效的选择性前列腺素E2受体激动剂,EC50值为2.8 nM。 了解更多
  18. KAG-308

    Catalog No. A18389
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    EP4 激动剂
    KAG-308, a newly-identified EP4-selective agonist shows efficacy for treating ulcerative colitis and can bring about lower risk of colorectal carcinogenesis by oral administration. 了解更多
  19. PF-04418948

    Catalog No. A12894
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    EP2 Receptor 拮抗剂
    PF-04418948是一种有效的选择性前列腺素EP2受体拮抗剂,IC50为16 nM。 了解更多
  20. MF498

    Catalog No. A15532
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    EP4 receptor 拮抗剂
    MF498是一种新型的选择性E前列腺素类受体4(EP4受体)拮抗剂,对EP4受体具有很强的结合亲和力,Ki为0.7 nM。 了解更多
  21. GW627368

    Catalog No. A15525
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    EP4 receptor 拮抗剂
    GW627368是一种新型,有效且选择性的前列腺素EP4受体竞争拮抗剂(Ki = 100 nM),具有额外的人TP受体亲和力(Ki = 150 nM)。 了解更多
  22. Saikosaponin B2

    Catalog No. A14600
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    Prostanoid activator
    Saikosaponin B2是皂苷激活剂。 了解更多
  23. NS-304 (Selexipag)

    Catalog No. A13880
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    prostacyclin receptor 激动剂
    NS-304 (Selexipag)是一种选择性的前列环素IP1受体激动剂(人和大鼠IP受体的Ki值为260和2100 nM,EP1-4,DP,FP和TP受体的Ki值为> 10μM)。 了解更多
  24. BAY-u 3405

    Catalog No. A13751
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    dual 拮抗剂 of TP/DP2
    BAY-u 3405是用于治疗变应性鼻炎的经过批准的人用药物,已证明其具有作为血栓烷受体(TP受体)的拮抗剂的活性。 了解更多
  25. Cloprostenol (sodium salt)

    Catalog No. A13498
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    cloprostenol是前列腺素F2α(PGF2α)的合成类似物。它在仓鼠和大鼠中终止妊娠的效力分别是PGF2α的200倍和100倍,而没有与PGF2α相关的副作用。 了解更多
  26. MK-2894

    Catalog No. A11497
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    EP4 receptor 拮抗剂
    MK-2894是一种高度有效和选择性的第二代EP4拮抗剂。 了解更多
  27. Ozagrel hydrochloride

    Catalog No. A11742
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    Thromboxane A2 synthesis 抑制剂
    Ozagrel hydrochloride是一种抗血小板剂,用作血栓烷a2合成抑制剂。 了解更多
  28. Laropiprant (MK0524)

    Catalog No. A11483
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    DP1 抑制剂
    Laropiprant (MK0524)与烟酸合用可降低血液胆固醇。是一种有效的,选择性的 DP receptor 拮抗剂,Ki 值为 0.57 nM,对 TP 受体的 Ki 值为 2.95 nM。 了解更多

28 个项目