VDA

Inhibitory Selectivity
Catalog No.Inhibitor Name VDAOther
A10324DMXAA (ASA404, Vadimezan)
**
A10654NPI-2358 (Plinabulin)
***
A12658Verteporfin
YAP/TEAD interaction

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. DMXAA (ASA404, Vadimezan)

    Catalog No. A10324
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    Vascular Disrupting Agent (VDA)
    DMXAA (ASA404,Vadimezan)是一种肿瘤血管破坏剂(tumor-VDA),也是一种DT-diaphorase的竞争性抑制剂。 了解更多
  2. Verteporfin

    Catalog No. A12658
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    YAP 抑制剂
    Verteporfin是抑制TEAD-YAP缔合和YAP诱导的肝过度生长的小分子。它也是一种有效的第二代光敏剂,衍生自卟啉。 了解更多
  3. NPI-2358 (Plinabulin)

    Catalog No. A10654
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    Microtubule 抑制剂
    NPI-2358 (Plinabulin)是NPI-2350的合成类似物,NPI-2350是从曲霉属(Aspergillus sp.)分离的天然产物,可解聚A549人肺癌细胞中的微管。 了解更多
  4. Oxi 4503

    Catalog No. A14352
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    VDA
    Oxi4503是一种新型血管靶向剂,与康普他汀A-4磷酸酯相比,对血流和抗肿瘤活性有影响。 了解更多

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