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微信关注Farnesyl Transferase
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| Catalog No. | Product Name | Application | Product Information |
|---|---|---|---|
A12328 |
Lonafarnib (SCH66336) |
FPTase 抑制剂 |
Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
|
A15796 |
L-778123 HCl
|
FPTase 抑制剂 |
L-778123 HCl is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM in enzyme inhibition determination.
|
A10935 SALE |
Tipifarnib (Zarnestra) |
FTase 抑制剂 |
Tipifarnib (Zarnestra) is a farnesyltransferase inhibitor that inhibits the Ras kinase in a post translational modification step before the kinase pathway becomes hyperactive.
|
A12368 |
FTI 277 |
FTase 抑制剂 |
FTI 276 is an inhibitor that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10 μM respectively) and disrupts constitutive H-Ras-specific actvation of MAPK. Causes significant antiproliferative effects in human malignant glioma cells and many other tumor cell lines.
|
A14020 SALE |
LB42708 |
FTase 抑制剂 |
LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhibitor (FTase inhibitor).
|
A14439 |
FTI-277 HCl |
FTase 抑制剂 |
FTI-277 HCl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.
|
6 个项目
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