DNA Damage

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  1. Saccharin 1-methylimidazole

    Catalog No. A16114
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    DNA and RNA synthesis activator
    Saccharin 1-methylimidazole被认为是DNA和RNA合成的通用活化剂。 了解更多
  2. SRT1720 HCl

    Catalog No. A10862
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    SIRT1 Activator
    SRT1720 HCl是一种抑制剂,旨在作为瑟土因亚型SIRT1的小分子活化剂。 了解更多
  3. SRT 1720

    Catalog No. A15247
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  4. SRT2104 (GSK2245840)

    Catalog No. A14188
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    SIRT1 activator
    SRT2104 (GSK2245840)是一种选择性sirt1激活剂,参与能量稳态的调节。 了解更多
  5. Tenovin-6

    Catalog No. A12305
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    p53 activator
    Tenovin-6是tenovin-1的类似物。Tenovin-6在体外抑制纯化的人SIRT1、SIRT2和SIRT3的蛋白脱乙酰酶活性,IC50值分别为21、10和67 uM。 了解更多
  6. CAY10602

    Catalog No. A19395
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    SIRT1 activator
    CAY10602 is a SIRT1 activator. 了解更多
  7. SRT 2183

    Catalog No. A12150
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    Sirtuin-1 (SIRT1) activator
    SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels. 了解更多
  8. SRT 1460

    Catalog No. A19026
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    SIRT1 activator
    SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues. 了解更多
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    MDL-800

    Catalog No. A17228
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    SIRT6 allosteric activator
    MDL-800 is a first-in-class cellularly active SIRT6 allosteric activator. 了解更多
  9. SRT 1720 Hydrochloride

    Catalog No. A21143
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    SIRT1 activator of
    SRT 1720 Hydrochloride is a selective activator of SIRT1 with an EC50 of 0.10 μM, and shows less potent activities on SIRT2 and SIRT3. 了解更多
  10. UBCS039

    Catalog No. A18961
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    SIRT6 activator
    UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM. 了解更多

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