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Integrin
Catalog No. | Product Name | Application | Product Information |
---|---|---|---|
A11614 |
Zaurategrast (CDP323) |
VCAM-1 拮抗剂 |
CDP323 is a small-molecule prodrug antagonist of the vascular cell adhesion molecule 1 binding to ??4-integrins
|
A15918 |
Cyclo(RGDyK) |
Integrin 抑制剂 |
Cyclo(RGDyK) is a potent and selective alphaVbeta3 integrin inhibitor with IC50 of 20 nM.
|
A15456 SALE |
E7820 |
lpha-2-integrin 抑制剂 |
E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells.
|
A15538 |
RGD (Arg-Gly-Asp) Peptides |
Inhibits integrin binding to RGD motifs |
RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
|
A14923 |
Cyclo (-RGDfK) |
??v??3 integrin 抑制剂 |
Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.
|
A13968 |
Leukadherin 1 |
Integrin 激动剂 |
Leukadherin 1 is an allosteric activator of CD11b/CD18. Increases CD11b/CD18-dependent cell adhesion to fibrinogen (EC50 = 4 μM).
|
A12876 |
Pyrintegrin |
- |
Pyrintegrin is a cell-permeable small molecule that promotes human embryonic stem cell (hESC) survival by > 30-fold.
|
A12787 SALE |
Firategrast (SB 683699) |
??4??1/??4??7 integrin 拮抗剂 |
Firategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS).
|
A12371 |
Cilengitide trifluoroacetate |
Integrin 抑制剂 |
Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
|
A12372 SALE |
Cilengitide |
- |
Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
|
A15967 |
CWHM12 |
??V integrins 抑制剂 |
CWHM 12 can suppress all 5 alpha V integrins. CWHM12 not only worked the same way to prevent fibrosis as the genetic deletion method, it also prevent the progression of existing fibrosis in the liver and lungs and reversed some of the damage caused by fibrosis to those organs.
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