β-catenin

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  1. Longdaysin

    Catalog No. A21022
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    Wnt/??-catenin signaling inhibitor
    Longdaysin is a inhibitor of the Wnt/β-catenin signaling pathway, which exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling. 了解更多
  2. SKL2001

    Catalog No. A16707
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    Wnt/β-catenin agonist
    SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction. 了解更多
  3. HLY78

    Catalog No. A18402
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    Wnt/β-catenin 激活剂
    HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction. 了解更多
  4. Wnt/β-catenin agonist 1

    Catalog No. A18689
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    Wnt/β-catenin 激动剂
    Wnt/β-catenin agonist 1 is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM. 了解更多
  5. IWP-4

    Catalog No. A17004
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    Wnt/β-catenin signaling 抑制剂
    IWP-4是Wnt /β-catenin信号传导的新型有效抑制剂。 了解更多
  6. iCRT3

    Catalog No. A16847
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    Wnt/β-catenin 拮抗剂
    iCRT3是Wnt /β-catenin信号的拮抗剂,在Wnt反应性STF16-luc报告基因检测中,IC50为8.2 nM。 了解更多
  7. KYA1797K

    Catalog No. A16353
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    Wnt/beta-catenin 抑制剂
    KYA1797K是一种高效且选择性的Wnt/β-catenin抑制剂,IC50为0.75 μM(TOPflash分析)。 了解更多
  8. iCRT 14

    Catalog No. A16218
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    CRT 抑制剂
    iCRT 14是一种新型的有效的β-catenin反应转录(CRT)抑制剂(在Wnt途径活性测定中IC50 = 40.3 nM)。 了解更多
  9. Hexachlorophene

    Catalog No. A16217
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    Wnt/beta-catenin 抑制剂
    Hexachlorophene是一种有效的KCNQ1/KCNE1钾通道激活剂,EC50为4.61±1.29 uM。也是Wnt/β-catenin信号的抑制剂。 了解更多
  10. Cardiogenol C HCl

    Catalog No. A16198
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    Cardiogenol C HCl是一种二氨基嘧啶化合物,可诱导MHC-(肌球蛋白重链)阳性心肌细胞从胚胎干细胞中分化出来,EC50值为0.1 uM。心源醇C上调心脏标志物并诱导沿袭定型祖细胞的心脏功能特性。 了解更多
  11. IQ-1

    Catalog No. A16064
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    Wnt/beta-catenin 抑制剂
    IQ-1是可透过细胞的四氢异喹啉亚基化合物,可调节Wnt/β-catenin信号传导。 了解更多
  12. PRI-724

    Catalog No. A15856
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    CBP/beta-catenin 拮抗剂
    PRI-724是ICG-001的异构体或对映异构体,是一种强力的特异性抑制剂癌症干细胞中的Wnt信号通路具有潜在的抗肿瘤活性。 了解更多
  13. Cardiogenol C hydrochloride

    Catalog No. A15773
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    Cardiogenol C hydrochloride是心肌细胞中胚胎干细胞分化的有效且可渗透细胞的诱导剂,显示Ec50为100nm。 了解更多
  14. BC2059

    Catalog No. A14381
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    beta-catenin inhibitor
    BC2059 is an orally bioavailable and potent beta-catenin inhibitor. 了解更多
  15. WAY-316606

    Catalog No. A13986
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    sFRP-1 抑制剂
    WAY-316606是分泌蛋白sFRP-1的小分子抑制剂,sFRP-1是分泌糖蛋白Wnt的内源性拮抗剂。 了解更多
  16. FH535

    Catalog No. A13795
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  17. IWR-1-endo

    Catalog No. A12737
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    Wnt 抑制剂
    IWR-1-endo是Wnt应答的有效抑制剂,可阻断基于细胞的Wnt /β-catenin途径报道分子应答,IC50值为180 nM。 Wnt蛋白与细胞表面的受体结合,启动信号级联反应,从而导致β-catenin激活基因转录。 了解更多
  18. ICG-001

    Catalog No. A11039
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    Wnt/beta-catenin 抑制剂
    ICG-001是Wnt/β-catenin信号传导途径的特异性抑制剂,可抑制β-catenin/环状AMP响应元件结合(CREB)蛋白的转录(IC50 = 3 uM)。 了解更多

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