Metabotropic glutamate receptors (mGluR)

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  1. CBiPES HCl

    Catalog No. A15811
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    mGlu2 receptor modulator
    CBiPES HCl是mGluR-2的选择性正变构调节剂,IC50值为98.2 nM。 了解更多
  2. CPPHA

    Catalog No. A15053
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    mGluR1 modulator
    CPPHA是mGluR5受体的选择性正变构调节剂。 了解更多
  3. BMT-145027

    Catalog No. A12457
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    mGluR5 positive allosteric modulator
    BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM. 了解更多
  4. Lu AF21934

    Catalog No. A12140
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    mGlu4 receptor modulator
    Lu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4. 了解更多
  5. TCN238

    Catalog No. A21191
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    mGlu4 receptor modulator
    TCN238 is a positive allosteric mGlu4 receptor modulator with an EC50 of 1 μM. 了解更多
  6. Basimglurant

    Catalog No. A21225
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    mGlu5 negative allosteric modulator
    Basimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. 了解更多
  7. (R)-ADX-47273

    Catalog No. A21887
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    mGluR5 positive allosteric modulator
    (R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . 了解更多
  8. VU0652835

    Catalog No. A18885
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    mGlu5 modulator
    VU0652835 is a metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 of 81 nM. 了解更多
  9. VU 0364770

    Catalog No. A12139
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    mGlu4 receptors modulator
    VU 0364770是mGlu4受体的正变构调节剂,在表达mGlu4的HEK 293细胞中EC50值为290 nM。 了解更多
  10. ADX-47273

    Catalog No. A11181
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    mGluR5 modulator
    ADX-47273是一种有效的,特异性的mGlu5正变构调节剂(PAM)EC50为0.17 μM,对其他亚型没有作用活性。 了解更多
  11. BINA

    Catalog No. A11126
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    mGluR2 modulator
    BINA是mGlu2的选择性正构构调节剂(在表达人mGlu2的CHO细胞中EC50 = 33.2 nM)。 了解更多
  12. VU 0364439

    Catalog No. A12664
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    GluR modulator
    VU 0364439是mGlu4受体的正变构调节剂(PAM)(对于人mGlu4,体外EC50 = 19.8 nM)。 了解更多
  13. VU 0361737

    Catalog No. A12467
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    mGlu4 receptors modulator
    VU 0361737是mGluR-4的选择性正变构调节剂(人和大鼠受体的EC50值分别为240和110 nM)。 了解更多
  14. JNJ 42153605

    Catalog No. A14330
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    mGluR-2 modulator
    JNJ-42153605是亲代谢型谷氨酸2受体的正变构调节剂。 了解更多
  15. VU0364289

    Catalog No. A15832
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    mGluR5 Modulator
    VU0364289是新型N-芳基哌嗪mGlu5阳性变构调节剂。 了解更多

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