Isocitrate Dehydrogenase (IDH)

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  1. AGI-6780

    Catalog No. A12903
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    IDH2 R140Q 抑制剂
    AGI-6780是有效的选择性IDH2突变抑制剂,IC50值为23 nM。 了解更多
  2. IDH-C227

    Catalog No. A12923
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    IDH1 R132H 抑制剂
    IDH-C227是一种有效的选择性IDH1 R132H抑制剂。 了解更多
  3. Enasidenib

    Catalog No. A15808
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    IDH2 抑制剂
    Enasidenib是一种有效的选择性IDH2抑制剂,具有潜在的抗癌活性(IDH2 =异柠檬酸脱氢酶2)。 了解更多
  4. AG-120 (Ivosidenib)

    Catalog No. A14386
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    IDH1 抑制剂
    AG-120 (Ivosidenib)是1型异柠檬酸脱氢酶(IDH1)的口服抑制剂,具有潜在的抗肿瘤活性。 了解更多
  5. IDH-305

    Catalog No. A16943
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    IDH1 抑制剂
    IDH305是柠檬酸循环酶异柠檬酸脱氢酶[NADP]细胞质的抑制剂(异柠檬酸脱氢酶1,IDH1),在残基R132(IDH1(R132))处具有突变,具有潜在的抗肿瘤活性。 了解更多
  6. Vorasidenib

    Catalog No. A16908
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    IDH1 抑制剂
    Vorasidenib (AG-881)是一种有效且选择性的口服抑制剂,可抑制细胞质中异柠檬酸脱氢酶1型(IDH1,IDH1 [NADP+]可溶)和2型(IDH2异柠檬酸脱氢酶[NADP+])的突变形式。线粒体中的线粒体,具有潜在的抗肿瘤活性。 了解更多
  7. BAY-1436032

    Catalog No. A17059
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    mIDH1 抑制剂
    BAY-1436032是一种有效的,选择性的,口服的突变型异柠檬酸脱氢酶1(mIDH1)抑制剂。 了解更多
  8. Olutasidenib (FT-2102)

    Catalog No. A18789
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    IDH1 inhibitor
    Olutasidenib is a potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 for the treatment of acute myeloid leukemia. 了解更多
  9. Mutant IDH1-IN-4

    Catalog No. A19106
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    IDH1 inhibitor
    Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ?? 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells. 了解更多
  10. IDH1 Inhibitor 2

    Catalog No. A18420
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    IDH1 inhibitor
    DH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM. 了解更多

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