Adenosine Receptors

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  1. Pentostatin

    Catalog No. A11534
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    Adenosine deaminase 抑制剂
    Pentostatin是腺苷脱氨酶的不可逆抑制剂(Ki = 2.5 pM)。 了解更多
  2. MT-DADMe-ImmA

    Catalog No. A13651
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    human 5'-methylthioadenosine phosphorylase inhibitor
    MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP) with a Ki of 90 pM. 了解更多
  3. A2A receptor antagonist 1

    Catalog No. A12567
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    adenosine A2A/A1 receptor antagonist
    A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively. 了解更多
  4. AB-MECA

    Catalog No. A12189
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    A3 adenosine receptor agonist
    AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors. 了解更多
  5. CGS 21680

    Catalog No. A11354
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    adenosine A2A receptor agonist
    CGS 21680 is a selective adenosine A2A receptor agonist, with a Ki of 27 nM. 了解更多
  6. APNEA

    Catalog No. A20845
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    A3 adenosine receptor agonist
    APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine) is a potent, non-selective A3 adenosine receptor agonist. 了解更多
  7. LAS101057

    Catalog No. A21203
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    A2B receptor antagonist
    LAS101057 is a potent, selective, and orally efficacious A2B receptor antagonist. 了解更多
  8. Reversine

    Catalog No. A13250
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    human A3 adenosine receptor 拮抗剂 /Aurora 抑制剂
    Reversine是一种有效的人A3腺苷受体拮抗剂,Ki为0.66μM,是一种泛光A/B/C激酶抑制剂,IC50分别为12 nM/13 nM/20 nM。也用于干细胞去分化。 了解更多
  9. Tonapofylline

    Catalog No. A21328
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    adenosine A1 receptor antagonist
    Tonapofylline (BG 9928) is an orally active and selective adenosine A1 receptor antagonist with a Ki of 7.4 nM for human adenosine A1 receptor (hA1), which displays 915-fold selectivity versus human adenosine A2A receptor and 12-fold selectivity versus human adenosine A2B receptor and is used in development for the treatment of heart failure. 了解更多
  10. LUF6000

    Catalog No. A21532
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    A3 adenosine receptor allosteric modulator
    LUF6000 is an allosteric modulator of the human A3 adenosine receptor (AR). 了解更多
  11. EHNA hydrochloride

    Catalog No. A21585
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    Adenosine deaminase inhibitor
    EHNA hydrochloride is a specific inhibitor of adenosine deaminase, prevents dAdo degradation and increases mitochondrial dATP levels in fibroblasts. 了解更多
  12. Rolofylline

    Catalog No. A21649
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    adenosine A1 receptor antagonist
    Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment. 了解更多
  13. Derenofylline

    Catalog No. A21990
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    adenosine A1 receptor antagonist
    Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. 了解更多
  14. MRS 1754

    Catalog No. A21998
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    A2B adenosine receptor antagonist
    MRS 1754 is a selective antagonist radioligand for A2B adenosine receptor with very low affinity for A1 and A3 receptors of both humans and rats. 了解更多
  15. N6-Cyclohexyladenosine

    Catalog No. A21008
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    A1 receptor agonist
    N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM). 了解更多
  16. MRS1177

    Catalog No. A16871
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    Adenosine A3 receptor 拮抗剂
    MRS1177是一种有效的选择性人腺苷A3受体(hA3AR)拮抗剂,Ki为0.3 nM。 了解更多
  17. MRS1186

    Catalog No. A16870
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    Adenosine A3 receptor 拮抗剂
    MRS1186是一种有效的选择性人腺苷A3受体(hA3AR)拮抗剂,Ki为7.66 nM。 了解更多
  18. NECA

    Catalog No. A16962
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    adenosine receptor 激动剂
    NECA是一种高亲和力的腺苷受体激动剂(human A3,A1和A2A受体的Ki值分别为6.2、14和20 nM;human A2B的EC50 = 2.4 μM)。 了解更多
  19. AZD-4635 (HTL1071)

    Catalog No. A16820
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    A2AR 拮抗剂
    AZD-4635 (HTL1071)是一种口服A2AR拮抗剂,可与人A2AR结合,Ki为1.7 nM,选择性比其他腺苷受体高30倍。 了解更多
  20. Proxyphylline

    Catalog No. A16821
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    A1 adenosine receptors 拮抗剂
    Proxyphylline是茶碱的衍生物,由于其心血管特性而被用作支气管扩张剂。它与A2腺苷受体(对于血小板,Ki = 850μM)选择性拮抗A1腺苷受体(对于牛脑,Ki = 82 nM)。 了解更多
  21. MRS1706

    Catalog No. A16868
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    adenosine A2B receptor 反向激动剂
    MRS1706是一种选择性腺苷A2B受体反向激动剂,对人A2B,A1,A2A和A3受体的Ki值分别为1.39、157、112和230 nM。 了解更多
  22. BAY-545

    Catalog No. A20116
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    A2B adenosine receptor antagonist
    BAY-545 is a potent and selective A2B adenosine receptor antagonist, with an IC50 of 59 nM. 了解更多
  23. ST3932

    Catalog No. A12880
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    Adenosine A2A receptor antagonist
    ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. 了解更多
  24. Tecadenoson

    Catalog No. A13302
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    A1 adenosine receptor agonist
    Tecadenoson (CVT-510) is a selective A1 adenosine receptor agonist. 了解更多
  25. CPI-444

    Catalog No. A19242
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    A2AR antagonist
    CPI-444 is a potent, oral and selective A2A receptor (A2AR) antagonist, which induces antitumor responses. 了解更多
  26. Istradefylline (KW-6002)

    Catalog No. A11451
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    A2A 拮抗剂
    Istradefylline (KW-6002)是A2A受体的选择性拮抗剂。 了解更多
  27. SYN-115 (Tozadenant)

    Catalog No. A11560
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    A2a receptor 拮抗剂
    SYN115是口服,有效和选择性的腺苷2a(A2a)受体抑制剂,作用于人类和恒河猴的 adenosine A2A 受体,Ki 值分别为 11.5 nM 和 6 nM。 了解更多
  28. CGS 21680 HCl

    Catalog No. A11619
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    Adenosine A2A Receptor 激动剂
    CGS 21680 HCl是一种特定的腺苷A2A亚型受体激动剂。 了解更多
  29. Adenosine

    Catalog No. A10040
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    Adenosine在生化过程中起着重要作用,例如能量转移(如三磷酸腺苷(ATP)和二磷酸腺苷(ADP))以及信号传导中的环状单磷酸腺苷cAMP。 它也是一种抑制性神经递质。 了解更多
  30. Aminophylline

    Catalog No. A10066
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    Adenosine receptor 拮抗剂
    Aminophylline是一种非选择性的腺苷受体拮抗剂和磷酸二酯酶抑制剂,能够逆转局部缺血引起的bradyasystole。 了解更多
  31. Dyphylline

    Catalog No. A10339
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    Adenosine receptor 拮抗剂
    Dyphylline是黄嘌呤衍生物,具有支气管扩张药和血管扩张药的作用。 它充当腺苷受体拮抗剂和磷酸二酯酶抑制剂。 了解更多
  32. SCH 442416

    Catalog No. A12695
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    A2A Receptor 拮抗剂
    SCH 442416是一种选择性的腺苷A2A受体拮抗剂。以高亲和力结合人和大鼠A2A受体(Ki值分别为0.048和0.5 nM)。在体外对hA2A的选择性比hA1高> 23000倍,并且对hA2B和hA3受体的亲和力最小(IC50> 10μM)。 了解更多
  33. Tamsulosin hydrochloride

    Catalog No. A12846
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    Tamsulosin hydrochloride是前列腺素α1A肾上腺素受体的拮抗剂。 了解更多
  34. CVT 6883

    Catalog No. A13745
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    adenosine A2B receptors 拮抗剂
    CVT-6883是一种选择性的A2B腺苷拮抗剂,代表了一种治疗心肺疾病的新型潜在方法。 了解更多
  35. Capadenoson

    Catalog No. A14159
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    Adenosine Receptor 激动剂
    Capadenoson是腺苷A1受体的选择性激动剂。 了解更多
  36. 5-Iodotubercidin

    Catalog No. A13948
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    Adenosine kinase 抑制剂
    5-Iodotubercidin是一种有效的腺苷激酶抑制剂,IC50为26 nM。 了解更多
  37. CF-102

    Catalog No. A14402
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    Adenosine A3 receptor 激动剂
    CF-102是具有潜在抗肿瘤活性生物利用的,合成的,高度选择性的腺苷A3受体(A3AR)激动剂。 了解更多
  38. CGS-15943

    Catalog No. A14327
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    Adenosine A Receptor 拮抗剂
    CGS 15943是一种有效的非选择性腺苷A受体拮抗剂。 了解更多
  39. IB-MECA

    Catalog No. A14345
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    Adenosine A3-R 激动剂
    IB-MECA已被证明是一种有效的选择性腺苷A3-R激动剂,腺苷A3-R,腺苷A1-R和腺苷A2A-R的Ki值分别为1.1、54和56 nM。 了解更多
  40. ZM-241385

    Catalog No. A13517
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    Adenosine A2A 拮抗剂
    ZM-241385是一种强效且高度选择性的腺苷A2A-R拮抗剂,在心脏血管中腺苷A2A-R的pA2为9.02,相对于腺苷A1-R,腺苷A2B-R和腺苷A3-的选择性分别为1000、91和500,000。 R个站点,分别。 了解更多
  41. Preladenant

    Catalog No. A13504
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    Adenosine A2A receptor 拮抗剂
    Preladenant是腺苷A2A受体的有效和选择性拮抗剂。 了解更多
  42. SCH58261

    Catalog No. A15886
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    A2A adenosine receptor 拮抗剂
    SCH58261是一种有效的选择性A2a腺苷受体拮抗剂,对大鼠A2a和牛A2a的Ki分别为2.3 nM和2 nM。 了解更多
  43. DPCPX

    Catalog No. A16104
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    Adenosine A1-R 拮抗剂
    DPCPX是一种非常有效的选择性腺苷A1-R拮抗剂。它对腺苷A2A-R,腺苷A2B-R和腺苷A3-R的功效非常适中。 了解更多
  44. 2-Chloroadenosine (CADO)

    Catalog No. A16105
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    Adenosine A Receptor 激动剂
    2-Chloroadenosine (CADO)是腺苷的代谢稳定的类似物,其表现为腺苷A受体激动剂(腺苷A1-R,腺苷A2A-R和腺苷A3-R的Ki值分别为300、80和1900 nM)。 了解更多
  45. CGS 21680 HCl

    Catalog No. A16441
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    Adenosine A2 receptor 激动剂
    CGS 21680 HCl是腺苷A2受体激动剂,IC50为22 nM,比A1受体高140倍。 了解更多
  46. Regadenoson

    Catalog No. A12541
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    A2A adenosine 激动剂
    Regadenoson是A2A腺苷受体相对于A1,A2B和A3受体的选择性激动剂。还发现Regadenoson是引起冠状动脉血管扩张的完全而有效的激动剂,这种反应具有非常大的A2A受体储备。 了解更多
  47. Vipadenant (BIIB-014)

    Catalog No. A13963
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    A2A receptor 拮抗剂
    Vipadenant,也称为BIIB014,CEB-4520,是针对帕金森氏症的有效,选择性和口服腺苷A2A受体拮抗剂。Vipadenant在帕金森氏病的常用模型中显示出强大的口服活性。 了解更多
  48. Theophylline-7-acetic acid

    Catalog No. A16822
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    Adenosine receptor 拮抗剂
    Theophylline-7-acetic acid是腺苷受体拮抗剂,是黄嘌呤类化学物质的兴奋剂。 了解更多

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