5-HT Receptors

产品 101 到 143 共 143个

每页
页面:
  1. 1
  2. 2
  3. 3

设置升序顺序
  1. Tandospirone

    Catalog No. A13293
    Quick View
    5-HT Receptor 拮抗剂
    Tandospirone是5HT1A受体的部分激动剂。它以剂量依赖性方式显着降低氟哌啶醇诱导的运动迟缓。 了解更多
  2. Bifeprunox Mesylate

    Catalog No. A14091
    Quick View
    Bifeprunox Mesylate是通过激活5-羟色胺5-羟色胺(5-HT)1A受体而产生的抗精神病药。 了解更多
  3. SB-742457

    Catalog No. A14092
    Quick View
    5-HT6 receptor 拮抗剂
    SB-742457是一种选择性的5-HT6受体拮抗剂,具有认知,记忆和增强学习的作用。 了解更多
  4. SB 399885 HCl

    Catalog No. A14102
    Quick View
    5-HT6 拮抗剂
    SB 399885 hydrochloride是一种有效的,脑渗透剂和口服活性的SR-6拮抗剂。它对SR-6的选择性比其他血清素受体高200倍(对于人类重组,天然大鼠和天然人类SR-6受体,pKi值分别为9.11、8.81和9.02)。 了解更多
  5. Cyclobenzaprine HCl

    Catalog No. A14255
    Quick View
    5-HT2 receptor 拮抗剂
    Cyclobenzaprine HCl是一种肌肉松弛剂,可阻止疼痛感。 了解更多
  6. Levomilnacipran HCl

    Catalog No. A14391
    Quick View
    serotonin/NE reuptake 抑制剂
    Levomilnacipran HCl是一种选择性的5-羟色胺和去甲肾上腺素再摄取抑制剂。 了解更多
  7. LuAE58054

    Catalog No. A14356
    Quick View
    5-HT6 receptor 拮抗剂
    LuAE58054是一种有效且选择性的5-HT6受体拮抗剂,Ki 为 0.83 nM。由伦德贝克(Lundbeck)开发,作为增强疗法,用于治疗与阿尔茨海默氏病和精神分裂症相关的认知缺陷。 了解更多
  8. Tropisetron HCL

    Catalog No. A14375
    Quick View
    5-HT3 receptor 拮抗剂
    Tropisetron HCL是选择性的5-HT3受体拮抗剂和α7烟碱样受体激动剂,对5-HT3受体的IC50为70.1±0.9 nM。 了解更多
  9. Flibanserin

    Catalog No. A13860
    Quick View
    Flibanserin是一种正在研究中用于预防女性HSDD的新药。是一种新型的多功能性五羟色胺受体激动剂和拮抗剂 (MSAA)。 了解更多
  10. Edivoxetine HCl

    Catalog No. A13865
    Quick View
    norepinephrine reuptake 抑制剂
    Edivoxetine HCl是一种选择性去甲肾上腺素再摄取抑制剂。 了解更多
  11. S 32212 HCl

    Catalog No. A13501
    Quick View
    5-HT2C 激动剂
    S 32212 HCl是5-HT2C受体的反向激动剂(人5-HT2C INI受体的pKi = 8.18)。 了解更多
  12. Norfluoxetine

    Catalog No. A13458
    Quick View
    serotonin uptake 抑制剂
    Norfluoxetine是抗抑郁药氟西汀的活性代谢物,抑制5-羟色胺的摄取,pKi值为7.35.1氟西汀的S-对映体的5-羟色胺再摄取阻断能力是R-对映体的20倍(pKis分别为7.86和6.51)。 了解更多
  13. NAN-190 hydrobromide

    Catalog No. A13417
    Quick View
    5-HT1A receptor 拮抗剂
    NAN-190 hydrobromide是一种广泛用于科学研究的药物和研究化学品。以前认为它是一种选择性的5-HT1A受体拮抗剂,但后来的发现表明它也能有效地阻断α2肾上腺素能受体。 了解更多
  14. Atomoxetine HCl

    Catalog No. A13424
    Quick View
    norepinephrine (NE) transporter 抑制剂
    Atomoxetine HCl是SLC6A2的一种竞争性特异性抑制剂,同时在大鼠下丘脑突触体中显示出微弱的ST和DAT抑制作用。 了解更多
  15. Clozapine N-oxide

    Catalog No. A15048
    Quick View
    5-HT1C receptor 拮抗剂
    Clozapine N-oxide是氯氮平的主要代谢产物,在体外可降低SR-2A(5-HT2血清素受体)密度。 了解更多
  16. Quetiapine

    Catalog No. A15216
    Quick View
    Quetiapine是一种非典型抗精神病药,用于治疗精神分裂症,双相I型躁狂症,双相II型抑郁症,双相I型抑郁症。 了解更多
  17. Ziprasidone

    Catalog No. A15286
    Quick View
    5-HT/dopamine receptor 拮抗剂
    Ziprasidone是5-HT(5-羟色胺)和多巴胺受体拮抗剂的组合,具有抗精神病活性。 了解更多
  18. Alosetron Hydrochloride

    Catalog No. A14989
    Quick View
    5HT3-receptor 拮抗剂
    Alosetron Hydrochloride是一种5-羟色胺5HT3受体拮抗剂,可用于治疗肠易激综合症。 了解更多
  19. Asenapine HCl

    Catalog No. A15002
    Quick View
    adrenergic receptor/5-HT receptor 抑制剂
    Asenapine hydrochloride抑制肾上腺素能受体(α1,α2A,α2B,α2C)的Ki为0.25-1.2 nM,还抑制5-HT受体(1A,1B,2A,2B,2C,5A,6、7),Ki为0.03- 4.0 nM。 了解更多
  20. Desvenlafaxine succinate hydrate

    Catalog No. A15491
    Quick View
    serotonin (5-HT)/norepinephrine (NE) reuptake 抑制剂
    Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白 和去甲肾上腺素(NE)转运蛋白重吸收抑制剂,Ki值分别为40.2 nM和558.4 nM 了解更多
  21. Tianeptine

    Catalog No. A11598
    Quick View
    Tianeptine是体外和体内5-HT摄取的选择性促进剂。 了解更多
  22. Pardoprunox HCl (SLV-308)

    Catalog No. A11538
    Quick View
    Pardoprunox HCl (SLV-308)是一种抗帕金森病药物,是多巴胺受体D2、D3和5-HT1A激动剂,用于治疗帕金森病。 了解更多
  23. Eptapirone

    Catalog No. A15923
    Quick View
    5HT(1A) receptor 激动剂
    Eptapirone是一种有效的,选择性的,高效的5-HT1A受体激动剂,具有显着的抗焦虑和抗抑郁潜力。 了解更多
  24. Pimavanserin

    Catalog No. A15884
    Quick View
    Serotonin2A Receptor Inverse 激动剂
    Pimavanserin是一种有效的选择性5-羟色胺5-HT2A反向激动剂,pIC50为8.73,用于治疗与帕金森氏病有关的精神病。 了解更多
  25. Cyproheptadine hydrochloride

    Catalog No. A16169
    Quick View
    serotonin/histamine2 拮抗剂
    Cyproheptadine hydrochloride是抗组胺药,是5-羟色胺和组胺的拮抗剂。 了解更多
  26. YL-0919

    Catalog No. A16337
    Quick View
    5-HT1A receptor 激动剂/serotonin reuptake 抑制剂
    YL0919,具有5-HT1A受体激动剂和选择性5-羟色胺再摄取抑制剂双重活性的新型抗抑郁候选药物,YL-0919抑制5-HT被大鼠大脑皮层突触小体和人重组细胞摄取的IC50值为1.78±0.34 nM和1.93±0.18 nM。 了解更多
  27. BRL-54443

    Catalog No. A15592
    Quick View
    5-HT1E/5-HT1F receptor 激动剂
    BRL 54443是5-HT1E和5-HT1F受体激动剂,pKi分别为8.7和9.25,对5-HT1A,5-HT1B,5-HT1D受体的结合亲和力较弱。 了解更多
  28. Buspirone HCl

    Catalog No. A15687
    Quick View
    5HT(1A) receptor 激动剂
    Buspirone hydrochloride是一种具有5-D(2)多巴胺能作用的血清素能(5HT(1A)受体激动剂)抗焦虑药,用于焦虑症。 了解更多
  29. Amitriptyline HCl

    Catalog No. A16404
    Quick View
    Amitriptyline HCl抑制5-羟色胺受体,去甲肾上腺素受体,5-HT4、5-HT2和sigma 1受体,IC50分别为3.45 nM,13.3 nM,7.31 nM,235 nM和287 nM。 了解更多
  30. Azasetron HCl

    Catalog No. A16417
    Quick View
    5-HT3 receptor 拮抗剂
    Azasetron HCl是一种选择性的5-HT3受体拮抗剂,IC50为0.33 nM,用于治疗癌症化学疗法引起的恶心和呕吐。 了解更多
  31. Eucalyptol

    Catalog No. A15662
    Quick View
    5-HT3 receptor 抑制剂
    Eucalyptol是一种在桉树和其他植物中发现的双环单萜。它是5-HT3受体,钾通道,TNF-α的抑制剂。和IL-1β。 了解更多
  32. LP-211

    Catalog No. A16898
    Quick View
    5-HT7 receptor 激动剂
    LP-211是血清素5-HT7受体的选择性激动剂,在大鼠克隆的5-HT7受体上的Ki值为0.58 nM,选择性是5-HT1A受体的300倍以上。 了解更多
  33. Temanogrel

    Catalog No. A17094
    Quick View
    5-HT(2A) receptor 激动剂
    Temanogrel,也称为APD791,是一种高度选择性的5-羟基色胺2A受体反向激动剂,正在开发中,用于治疗动脉血栓形成。 了解更多
  34. LY 334370 hydrochloride

    Catalog No. A17027
    Quick View
    5-HT1F 激动剂
    LY 334370 hydrochloride是一种选择性的5-HT1F受体激动剂(Ki值为1.87、16.4,> 100 (IC50))。CAS:199673-74-0(LY 334370盐酸盐);182563-08-2(LY 334370游离碱) 了解更多
  35. LY 344864 racemate

    Catalog No. A17015
    Quick View
    5-HT1F receptor 激动剂
    LY 344864 racemate是5-HT1F受体激动剂。 了解更多
  36. Volinanserin

    Catalog No. A17115
    Quick View
    5-HT2A receptor 拮抗剂
    Volananserin是高度选择性的5-HT2A受体拮抗剂。 了解更多
  37. Eptapirone (F-11440)

    Catalog No. A18338
    Quick View
    5-HT1A receptor agonist
    Eptapirone is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (pKi, 7.50), and somewhat lower than that of flesinoxan (pKi, 8.91). In vivo, F 11440 was 4- to 20-fold more potent than flesinoxan, and 30- to 60-fold more potent than buspirone. 了解更多
  38. Dolasetron

    Catalog No. A17595
    Quick View
    5-HT3 receptor antagonist
    Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. 了解更多
  39. Nefazodone hydrochloride

    Catalog No. A17622
    Quick View
    5-HT2 receptors inhibitor
    Nefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多
  40. Dolasetron Mesylate

    Catalog No. A17729
    Quick View
    5-HT3 receptor antagonist
    Dolasetron mesylate is a selective 5-HT3 receptor antagonist. 了解更多
  41. Alprenolol hydrochloride

    Catalog No. A17781
    Quick View
    5-HT1A receptor antagonist
    Alprenolol (hydrochloride) is a non-selective beta blocker as well as 5-HT1A receptor antagonist. 了解更多
  42. Pizotifen

    Catalog No. A18107
    Quick View
    5-HT receptor antagonist
    Pizotifen is a serotonin antagonist which acts mainly at the 5-HT1, 5-HT2A, and 5HT2C receptors with some antihistamine activity. 了解更多
  43. Alosetron (Hydrochloride(1:X))

    Catalog No. A11309
    Quick View
    Serotonin 5HT3-receptor antagonist
    Alosetron Hydrochloride(1:X) (GR 68755 Hydrochloride(1:X)) is a Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome. 了解更多

产品 101 到 143 共 143个

每页
页面:
  1. 1
  2. 2
  3. 3

设置升序顺序
Rewards