5-HT Receptors

产品 1 到 50 共 72个

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  1. SB 258585 HCl

    Catalog No. A14026
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    5-HT6 serotonin receptor 拮抗剂
    SB 258585 hydrochloride是一种选择性和有效的SR-6拮抗剂。该化合物显示出比其他5-羟色胺受体亚型高160倍的选择性。 了解更多
  2. Granisetron

    Catalog No. A15096
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    5-HT3 拮抗剂
    Granisetron是一种5-羟色胺5-HT3受体拮抗剂,可作为止吐药来治疗化疗后的恶心和呕吐。 了解更多
  3. WAY-100635 maleate salt

    Catalog No. A15282
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    5HT1A 拮抗剂
    WAY-100635 maleate salt是一种有效的、选择性的5-羟色胺1A拮抗剂,对5-HT的IC50为0.95-0.12 nM。 了解更多
  4. Piboserod

    Catalog No. A15542
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    5-HT4 receptor 拮抗剂
    Piboserod是一种选择性的5-HT(4)受体拮抗剂。 了解更多
  5. Ricasetron

    Catalog No. A15499
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    5-HT3 receptor 拮抗剂
    Ricasetron是在5-羟色胺5-HT3受体上充当选择性拮抗剂的药物。 了解更多
  6. LY278584

    Catalog No. A15500
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    5-HT3 拮抗剂
    LY278584是5-HT3受体的有效选择性拮抗剂。LY278584是研究大鼠脑内5-HT3受体定位的有用配体。 了解更多
  7. Lerisetron

    Catalog No. A15501
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    5HT3 receptor 拮抗剂
    Lerisetron是具有止吐活性的3型血清素(5-HT3)受体拮抗剂。 了解更多
  8. SB271046

    Catalog No. A15438
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    5-HT Receptor 拮抗剂
    SB271046 是一种有效的,选择性的5-HT6受体拮抗剂,pKi为8.9,与其他5-HT受体亚型相比,选择性高200倍。 了解更多
  9. Ketanserin tartrate

    Catalog No. A13664
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    5HT2A 拮抗剂
    Ketanserin tartrate是一种选择性的5-HT receptor拮抗剂。Ketanserin tartrate 也抑制 hERG 电流 (IhERG),IC50 为 0.11 μM。 了解更多
  10. GSK163090

    Catalog No. A15838
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    5-HT1A/B/D receptor 拮抗剂
    GSK163090是一种有效的,选择性的,活性的5-HT1A/B/D受体拮抗剂,对于5-HT1A/B/D和多巴胺D2/D3,pKi分别为9.4/8.5/9.7和6.3/6.7。 了解更多
  11. Flopropione

    Catalog No. A16550
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    5-HT1A receptor antagonist/COMT inhibitor
    Flopropione是5-HT1A受体拮抗剂,也是儿茶酚-邻甲基转移酶(COMT)抑制剂。 了解更多
  12. Deramciclane

    Catalog No. A13011
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    5-HT2A and 5-HT2C receptors antagonist
    Deramciclane has a high affinity for 5-HT2A and 5-HT2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2C receptors without direct stimulatory agonist. 了解更多
  13. lumateperone Tosylate

    Catalog No. A12279
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    5-HT2A receptor antagonist
    Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM). 了解更多
  14. 5-HT4 antagonist 1

    Catalog No. A12268
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    5-HT4 receptor antagonist
    5-HT4 antagonist 1 is a 5-HT4 receptor antagonist with a pKi of 9.6. 了解更多
  15. Ziprasidone hydrochloride monohydrate

    Catalog No. A11008
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    5-HT (serotonin) and dopamine receptor antagonist
    Ziprasidone hydrochloride monohydrate (CP 88059 hydrochloride monohydrate) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多
  16. Pancopride

    Catalog No. A12967
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    5-HT3 receptor antagonist
    Pancopride is a new potent and selective 5-HT3 receptor antagonist. 了解更多
  17. SB 271046 Hydrochloride

    Catalog No. A11573
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    5-HT6 receptor antagonist
    SB271046 Hydrochloride is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9. 了解更多
  18. WAY-100635 Maleate

    Catalog No. A16787
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    5-HT1A receptor antagonist
    WAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. 了解更多
  19. Ziprasidone hydrochloride

    Catalog No. A16790
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    5-HT (serotonin)/dopamine receptor antagonist
    Ziprasidone Hcl(CP-88059 Hcl) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多
  20. Sarpogrelate hydrochloride

    Catalog No. A17295
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    5-HT2 antagonist
    Sarpogrelate hydrochloride (MCI-9042), a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. 了解更多
  21. RS 127445

    Catalog No. A21256
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    5-HT2B receptor antagonist
    RS 127445 is a novel high affinity, selective 5-HT2B receptor antagonist with pKi of 9.5. 了解更多
  22. SB 242084 hydrochloride

    Catalog No. A21349
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    5-HT2C receptor antagonist
    SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. 了解更多
  23. Masupirdine mesylate

    Catalog No. A21409
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    5-HT6 receptor antagonist
    Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). 了解更多
  24. SB 242084

    Catalog No. A21715
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    5-HT2C receptor antagonist
    SB 242084 is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. 了解更多
  25. SB-269970 hydrochloride

    Catalog No. A21889
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    5-HT7 receptor antagonist
    SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors. 了解更多
  26. SB-224289 hydrochloride

    Catalog No. A21920
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    5-HT1B receptor antagonist
    SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect. 了解更多
  27. Ritanserin

    Catalog No. A21976
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    5-HT2 receptor antagonist
    Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors. 了解更多
  28. Eplivanserin mixture

    Catalog No. A21987
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    serotonin reuptake inhibitor/5-HT2A receptor antagonist
    Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, extracted from patent WO 2005/002578 A1. 了解更多
  29. Ziprasidone D8

    Catalog No. A21989
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    5-HT / dopamine receptor antagonist
    Ziprasidone D8 is deuterium labeled Ziprasidone, which is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多
  30. Agomelatine

    Catalog No. A10048
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    5-HT Receptor 拮抗剂
    Agomelatine是一种褪黑素激动剂(MT1和MT2受体)和5-HT2C拮抗剂。 了解更多
  31. LY310762

    Catalog No. A11106
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    5-HT Receptor 拮抗剂
    Y310762是5-HT1D的受体拮抗剂(EC50 = 31 nM)。 了解更多
  32. RS-127445

    Catalog No. A11165
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    5-HT2B receptor 拮抗剂
    RS-127445是5-羟色胺5-HT2B受体的有效和选择性拮抗剂,相对于密切相关的5-HT2A和5-HT2C受体具有约1000倍的选择性。 了解更多
  33. BRL-15572 dihydrochloride

    Catalog No. A11178
    5-HT1D receptor 拮抗剂
    BRL-15572是一种选择性的h5-HT1D拮抗剂,相对于h5-HT1B表现出60倍的选择性,对一系列其他受体类型的亲和力很小或没有亲和力。 了解更多
  34. WAY-100635

    Catalog No. A11182
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    5HT1A 拮抗剂
    WAY-100635最初被认为是选择性的5-HT1A受体拮抗剂,但随后的研究表明它也可作为D4受体的有效全效激动剂。 了解更多
  35. Naftopidil 2HCl

    Catalog No. A10619
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    5-HT1A and α1-adrenergic receptor 拮抗剂
    Naftopidil 2HCl是选择性5-HT1A和α1-肾上腺素能受体拮抗剂,IC50分别为0.1μM和0.2μM。 了解更多
  36. Puerarin (Kakonein)

    Catalog No. A10759
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    5-HT2C receptor 拮抗剂
    Puerarin (Kakonein)是几种已知的异黄酮之一。Puerarin是5-HT2C受体和苯二氮卓类拮抗剂。Puerarin正在研究作为一种自微乳化药物递送系统。 了解更多
  37. Tropisetron (ICS 205930)

    Catalog No. A11226
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    5-HT3 拮抗剂
    Tropisetron (ICS 205930)是5-羟色胺5-HT3受体拮抗剂,主要用作止吐药,用于治疗化疗后的恶心和呕吐。 了解更多
  38. Alosetron

    Catalog No. A11310
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    5-HT3 拮抗剂
    Alosetron是一种5-HT3拮抗剂,对胃肠道肠道神经系统的5-HT3受体具有拮抗作用。 了解更多
  39. SB269970 HCl

    Catalog No. A11925
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    5-HT7 receptor 拮抗剂
    SB269970 HCl是有效的选择性5-HT7受体拮抗剂。 了解更多
  40. Asenapine maleate

    Catalog No. A10091
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    H1 拮抗剂
    Asenapine maleate平对多种受体具有高亲和力(pKi),包括5-羟色胺5-HT1A(8.6),5-HT1B(8.4),5-HT2A(10.2),5-HT2B(9.8),5-HT2C(10.5),5 -HT5A(8.8),5-HT6(9.5)和5-HT7(9.9)受体,肾上腺素α1(8.9),α2A(8.9),α2B(9.5)和α2C(8.9)受体,多巴胺D1( 8.9),D2(8.9),D3(9.4)和D4(9.0)受体以及组胺H1(9.0)和H2(8.2)受体。 了解更多
  41. Ketanserin (Vulketan Gel)

    Catalog No. A10497
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    5-HT2A serotonin receptor 拮抗剂
    Ketanserin (Vulketan Gel)是大鼠和人5-HT2A血清素受体拮抗剂,Ki为2.5 nM。 了解更多
  42. Granisetron Hydrochloride

    Catalog No. A10437
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    5-HT3 receptor 拮抗剂
    Granisetron Hydrochloride是血清素5-ht3受体拮抗剂。 了解更多
  43. Mianserin hydrochloride

    Catalog No. A10588
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    5-HT2/5-HT1 拮抗剂
    Mianserin hydrochloride是5-HT2/5-HT1拮抗剂。对5-HT6非选择性5-HT2受体拮抗剂具有中等亲和力。对5-HT6具有中等亲和力。 了解更多
  44. Ondansetron HCl (GR 38032F)

    Catalog No. A10674
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    5-HT Receptors 拮抗剂
    Ondansetron HCl (GR 38032F)是5-羟色胺5-HT3受体拮抗剂,主要用作止吐药,通常在化疗后用于治疗恶心和呕吐。 了解更多
  45. Olanzapine (LY170053)

    Catalog No. A10667
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    5-HT Receptors/D2 dopamine receptor 拮抗剂
    Olanzapine (LY170053)对5-HT2血清素和D2多巴胺受体拮抗剂具有高亲和力。 了解更多
  46. Eletriptan

    Catalog No. A13075
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    5-HT1B receptor 激动剂
    Eletriptan是一种选择性5-羟色胺1B/1D(5-HT1B)受体激动剂。 了解更多
  47. 5-HT1A receptor 拮抗剂
    NAD 299 hydrochloride (Robalzotan)是一种选择性的,高亲和力的5-HT1A受体拮抗剂(体外Ki = 0.6 nM)。 了解更多
  48. Tropanserin

    Catalog No. A13767
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    5-HT3 receptor 拮抗剂
    tropanserin充当有效的选择性5-HT3受体拮抗剂。 了解更多
  49. SDZ 205-557 HCl

    Catalog No. A13766
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    5-HT4 Receptor 拮抗剂
    SDZ 205-557 HCl是一种有效的选择性5-HT4 5-羟色胺受体拮抗剂。 了解更多
  50. N-Desmethylclozapine

    Catalog No. A13762
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    5-HT2C serotonin receptor 拮抗剂
    N-Desmethylclozapine是一种有效的选择性5-HT2C血清素受体拮抗剂。 了解更多

产品 1 到 50 共 72个

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