Cell Metabolism

产品 251 到 300 共 623个

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  1. Rivaroxaban Diol

    Catalog No. A12411
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    Rivaroxaban Diol是恶唑烷酮衍生物,经优化可抑制凝血酶原酶复合物中结合的游离因子Xa和因子Xa。 了解更多
  2. Betrixaban

    Catalog No. A12518
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    FXa 抑制剂
    Betrixaban是一种抗凝血药,可作为直接Xa因子抑制剂。它具有强大的,口服活性和对因子Xa的高度选择性,由于其低hERG亲和力而从一组相似的化合物中选择。 了解更多
  3. ABT333

    Catalog No. A13878
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    NS5B 抑制剂
    ABT333是NS5B非核苷聚合酶抑制剂。 了解更多
  4. DPC-423

    Catalog No. A14099
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    factor Xa 抑制剂
    DPC423是一种高效且可口服生物利用的吡唑抗血栓形成剂。 了解更多
  5. Edoxaban (tosylate Monohydrate)

    Catalog No. A14317
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    Factor Xa 抑制剂
    Edoxaban (tosylate Monohydrate)是选择性Factor Xa抑制剂,Ki为0.561 nM。 了解更多
  6. 5-R-Rivaroxaban

    Catalog No. A14979
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    Factor Xa 抑制剂
    5-R-Rivaroxaban是利伐沙班的(R)对映异构体。利伐沙班是一种新型的口服直接Xa因子抑制剂,在晚期开发中用于预防和治疗血栓栓塞性疾病。 了解更多
  7. Edoxaban tosylate

    Catalog No. A15076
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    Factor Xa 抑制剂
    Edoxaban tosylate是临床预防卒中的口服Xa(FXa)抑制剂。 了解更多
  8. Rasagiline

    Catalog No. A11111
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    MAO B 抑制剂
    Rasagiline是MAO-B(单胺氧化酶-B)的选择性不可逆抑制剂。 了解更多
  9. Hordenine

    Catalog No. A10454
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    MAO-B 抑制剂
    Hordenine是一种苯乙胺生物碱,具有抗菌和抗生素特性。 了解更多
  10. Quercetin (Sophoretin)

    Catalog No. A10766
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    MAO-B 抑制剂
    Quercetin (Sophoretin)抑制许多酶系统,包括酪氨酸蛋白激酶,磷脂酶A2,磷酸二酯酶,线粒体ATPase,PI 3-激酶和蛋白激酶C。 了解更多
  11. Quercetin dihydrate (Sophoretin)

    Catalog No. A10765
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    MAO-B 抑制剂
    Quercetin dihydrate (Sophoretin)抑制许多酶系统,包括酪氨酸蛋白激酶,磷脂酶A2,磷酸二酯酶,线粒体ATPase,PI 3-激酶和蛋白激酶C。 了解更多
  12. Olodaterol

    Catalog No. A15761
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    MAO 抑制剂
    Olodaterol是一种长效的β肾上腺素受体激动剂,由Boehringer-Ingelheim生产,用于吸入治疗慢性阻塞性肺疾病(COPD)患者。 了解更多
  13. Pargyline hydrochloride

    Catalog No. A17288
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    MAO inhibitor
    Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. 了解更多
  14. Iproniazid

    Catalog No. A17445
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    MAO inhibitor
    Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent. 了解更多
  15. Molindone hydrochloride

    Catalog No. A17647
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    MAO inhibitor
    Molindone HCl is a D2 dopamine receptor antagonist. It also acts as a MAO inhibitor. 了解更多
  16. Minaprine dihydrochloride

    Catalog No. A17722
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    MAO-A inhibitor
    Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression. 了解更多
  17. Toloxatone

    Catalog No. A18043
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    MAO-A inhibitor
    Toloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor. Antidepressant. 了解更多
  18. Iproniazid phosphate

    Catalog No. A18135
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    MAO inhibitor
    Iproniazid phosphate is an irreversible inhibitor of monoamine oxidase types A and B that is used as an antidepressive agent. It has also been used as an antitubercular agent, but its use is limited by its toxicity. 了解更多
  19. TB5

    Catalog No. A13170
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    hMAO-B inhibitor
    TB5 is a potent, selective and reversible inhibitor of hMAO-B with a Ki value of 0.11??0.01 μM. 了解更多
  20. CX-157

    Catalog No. A12200
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    MAO-A inhibitor
    CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3?ng/mL. 了解更多
  21. Salsolidine

    Catalog No. A12969
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    MAO-A inhibitor
    Salsolidine is a tetrahydroisoquinoline alkaloid, acts as a stereoselective competitive MAO A inhibitor. 了解更多
  22. RS 8359

    Catalog No. A21240
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    MAO-A inhibitor
    RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity. 了解更多
  23. Lazabemide

    Catalog No. A21270
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    MAO-B inhibitor
    Lazabemide(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively). 了解更多
  24. Ro 41-1049 hydrochloride

    Catalog No. A21672
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    inhibitor of monoamine oxidase-A (MAO-A)
    Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (MAO-A). 了解更多
  25. Brofaromine

    Catalog No. A21777
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    MAO inhibitor
    Brofaromine (CGP 11305A) is a monoamine oxidase (MAO) inhibitor with IC50 of 0.2?μM for MAO-A. 了解更多
  26. Safinamide Mesylate (FCE28073)

    Catalog No. A10818
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    MAO 抑制剂
    Safinamide Mesylate是沙芬酰胺的甲磺酸盐,可选择性和可逆地抑制MAO-B,IC50为0.45μM。 了解更多
  27. Rasagiline mesylate

    Catalog No. A11722
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    Monoamine oxidase 抑制剂
    Rasagiline mesylate是一种不可逆的单胺氧化酶抑制剂,在早期帕金森氏病中用作单一疗法,在较晚期的病例中用作辅助疗法。对于B型MAO,它对A型的选择性是14倍。 了解更多
  28. SL251188

    Catalog No. A11777
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    MAO-B 抑制剂
    SL-251188是恶唑烷酮衍生物,在狒狒中被表征为放射性配体,可使用正电子发射断层扫描(PET)在体内可视化MAO-B。 了解更多
  29. Moclobemide

    Catalog No. A11885
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    MAO 抑制剂
    Moclobemide是单胺氧化酶A(MAO-A)的可逆和选择性抑制剂。 了解更多
  30. Bifemelane HCl

    Catalog No. A13353
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    MAO 抑制剂
    Bifemelane hydrochloride是抗抑郁的MAO抑制剂。逆转丁苯那嗪在小鼠中引起的僵直,并增加MPTP处理的mar猴的自发活动。 了解更多
  31. Tranylcypromine hydrochloride

    Catalog No. A13358
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    LSD1/BHC110 & MAO 抑制剂
    Tranylcypromine hydrochloride是一种非选择性的MAO-A/B抑制剂。 了解更多
  32. Safinamide

    Catalog No. A13294
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    MAO-B 抑制剂
    Safinamide是一种高度选择性和可逆的B型单胺氧化酶(MAO-B)抑制剂,可增加新纹状体多巴胺的浓度。 了解更多
  33. RN-1 2HCl

    Catalog No. A14344
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    MAO 抑制剂
    RN-1 2HCl对LSD1的选择性优于单胺氧化酶(MAO)-A和MAO-B(在辣根过氧化物酶偶联测定中,IC50值分别为70 nM,0.51和2.79 μM)。 了解更多
  34. Clorgyline hydrochloride

    Catalog No. A17357
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    monoamine oxidase A inhibitor
    Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) that is used in scientific research; structurally related to Pargyline. 了解更多
  35. Isocarboxazid

    Catalog No. A17887
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    monoamine oxidase inhibitor
    Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase, with an IC50 of 4.8 μM for rat brain monoamine oxidase in vitro. 了解更多
  36. Rasagiline 13C3 mesylate racemic

    Catalog No. A21350
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    Monoamine oxidase inhibitor
    Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase. 了解更多
  37. PAT-1251 Hydrochloride

    Catalog No. A21969
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    LOXL2 inhibitor
    PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively). 了解更多
  38. Methotrexate (Abitrexate)

    Catalog No. A10021
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    DHFR 抑制剂
    Methotrexate (Abitrexate)是一种抑制胸苷酸合成酶和从头嘌呤合成的细胞毒剂。 了解更多
  39. Pemetrexed disodium (Alimta)

    Catalog No. A10707
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    Pemetrexed disodium (Alimta)是一种新型抗叶酸和抗代谢药物,作用于TS,DHFR和GARFT。 了解更多
  40. Aminopterin

    Catalog No. A11787
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    Aminopterin是一种抗肿瘤药。它通过竞争二氢叶酸还原酶的叶酸结合位点而充当酶抑制剂。 了解更多
  41. Pemetrexed

    Catalog No. A12668
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    DHFR 抑制剂
    Pemetrexed 是一种具有多个靶标的新型抗叶酸药。作用于TS,DHFR和GARFT,Ki分别为1.3 nM,7.2 nM 和 65 nM。 了解更多
  42. Trimetrexate

    Catalog No. A12796
    Trimetrexate是喹唑啉衍生物。它是二氢叶酸还原酶抑制剂。 了解更多
  43. NSC 131463 (DAMPA)

    Catalog No. A10655
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    DHFR 抑制剂
    NSC 131463 (DAMPA)是有效的二氢叶酸还原酶抑制剂,IC50为1 nM。 了解更多
  44. Pralatrexate

    Catalog No. A11522
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    DHFR 抑制剂
    Pralatrexate是一种抗叶酸剂(叶酸类似物代谢抑制剂),设计用于优先在癌细胞中积累。 了解更多
  45. Pemetrexed disodium hemipenta hydrate

    Catalog No. A15207
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    Pemetrexed disodium hemipenta hydrate是TS,DHFR和GARFT的新型抗叶酸和抗代谢药,Ki分别为1.3 nM,7.2 nM和65 nM。 了解更多
  46. Diaveridine

    Catalog No. A17000
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    DHFR 抑制剂
    Diaveridine(EGIS-5645)是一种二氢叶酸还原酶(DHFR)抑制剂,其野生型DHFR的Ki值为11.5 nM,同时也是一种抗菌剂。 了解更多
  47. WR99210

    Catalog No. A18837
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    DHFR 抑制剂
    WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains. 了解更多
  48. CAY10566

    Catalog No. A16936
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    SCD1 抑制剂
    CAY10566是SCD1的强效和选择性抑制剂,在小鼠和人酶测定中的IC50值分别为4.5和26 nM。 了解更多
  49. A939572

    Catalog No. A13298
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    SCD1 inhibitor
    A939572 is a potent, and orally bioavailable stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. 了解更多
  50. CVT-12012

    Catalog No. A21447
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    SCD inhibitor
    CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively. 了解更多

产品 251 到 300 共 623个

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  3. 6
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