AG14361

目录号: A10046

PARP 抑制剂

AG14361

AG14361 Chemical Structure

CAS NO. 328543-09-5

AG14361是一种有效的PARP抑制剂,可在MMR(错配修复)有效/不足的细胞中增强替莫唑胺(TMZ)的细胞毒性。

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,700.00
50 mg
¥ 5,500.00
100 mg
¥ 9,000.00
10mM * 1mL in DMSO
¥ 1,230.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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AG14361是一种有效的PARP抑制剂,可在MMR(错配修复)有效/不足的细胞中增强替莫唑胺(TMZ)的细胞毒性。
靶点信息
PARP1 (Cell-free assay)
<5 nM(Ki)
In vitro (25°C) DMSO 12 mg/mL (37.45 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.21 mL 156.05 mL 312.11 mL
0.5 mM 6.24 mL 31.21 mL 62.42 mL
1 mM 3.12 mL 15.61 mL 31.21 mL
5 mM 0.62 mL 3.12 mL 6.24 mL

*The above data is based on the productmolecular weight 320.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10046
作用机制 Inhibitor (抑制剂)
M. Wt 320.4
Formula C19H20N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 328543-09-5
Synonyms AG-14361
SMILES CN(C)CC1=CC=C(C=C1)C2=NC3=CC=CC4=C3N2CCNC4=O

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