AZD-2461

目录号: A12393

PARP 抑制剂

AZD-2461

AZD-2461 Chemical Structure

CAS NO. 1174043-16-3

AZD2461是新型有效的PARP抑制剂,对P-糖蛋白的亲和力较低。

库存: 现货

规格 价格 数量
5 mg
¥ 550.00
10 mg
¥ 800.00
25 mg
¥ 1,500.00
100 mg
¥ 2,600.00
10mM * 1mL in DMSO
¥ 1,460.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AZD2461是新型有效的PARP抑制剂,对P-糖蛋白的亲和力较低。
靶点信息
PARP
In vitro (25°C) DMSO 79 mg/mL (199.78 mM)
Water <1 mg/mL (<1 mM)
Ethanol 31 mg/mL (78.39 mM)
In vivo 0.5% hydroxyethyl cellulose/0.1% Tween 80 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.29 mL 126.44 mL 252.89 mL
0.5 mM 5.06 mL 25.29 mL 50.58 mL
1 mM 2.53 mL 12.64 mL 25.29 mL
5 mM 0.51 mL 2.53 mL 5.06 mL

*The above data is based on the productmolecular weight 395.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12393
作用机制 Inhibitor (抑制剂)
M. Wt 395.43
Formula C22H22FN3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1174043-16-3
Synonyms AZD2461, AZD 2461
SMILES COC1CCN(CC1)C(=O)C2=C(C=CC(=C2)CC3=NNC(=O)C4=CC=CC=C43)F

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