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PARP 抑制剂

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产品目录号: A12393


产品名 目录号 价格 数量
AZD-2461 5mg A12393-5
¥ 900.00
AZD-2461 10mg A12393-10
¥ 1,600.00
AZD-2461 25mg A12393-25
¥ 3,000.00
AZD-2461 100mg A12393-100
¥ 7,200.00
AZD-2461 10mM * 1mL in DMSO A12393-10mM-D
¥ 1,460.00



AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A12393
Mechanism of action Inhibitor
分子量 395.43
化学分子式 C22H22FN3O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1174043-16-3
Synonyms AZD2461, AZD 2461
化学名称 4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one


AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein.


Solubility (25°C) * In vitro DMSO 79 mg/mL (199.78 mM)
Water <1 mg/mL (<1 mM)
Ethanol 31 mg/mL (78.39 mM)
In vivo 0.5% hydroxyethyl cellulose/0.1% Tween 80 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.29 mL 126.44 mL 252.89mL
0.5 mM 5.06 mL 25.29 mL 50.58 mL
1 mM 2.53 mL 12.64 mL 25.29 mL
5 mM 0.51 mL 2.53 mL 5.06 mL

*The above data is based on the productmolecular weight 395.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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