AZD-2461
目录号: A12393
PARP 抑制剂
AZD2461 是一种新型且高效的 PARP 抑制剂,其对 P-糖蛋白 的亲和力较低。
Discription | AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. | |||||
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Targets |
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Cell Research |
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目录号 | A12393 |
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分子式 | C22H22FN3O3 |
分子量 | 395.43 |
CAS号 | 1174043-16-3 |
SMILES | COC1CCN(CC1)C(=O)C2=C(C=CC(=C2)CC3=NNC(=O)C4=CC=CC=C43)F |
其他名称 | AZD2461, AZD 2461 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 73 mg/mL (184.61 mM) | |
Water | Insoluble | ||
Ethanol | 29 mg/mL (73.33 mM) | ||
In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.29 mL | 126.44 mL | 252.89 mL |
0.5 mM | 5.06 mL | 25.29 mL | 50.58 mL |
1 mM | 2.53 mL | 12.64 mL | 25.29 mL |
5 mM | 0.51 mL | 2.53 mL | 5.06 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2