GeA-69
目录号: A19705
PARP14 抑制剂
GeA-69 是一种选择性的、高度细胞渗透性的 多腺苷二磷酸核糖聚合酶 14 (PARP14) 的 变构抑制剂，针对 宏域 2，其 Kd 为 2.1 微摩尔。
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生物活性
| Discription | GeA-69 is a selective, highly cell permeable allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2, with a Kd of 2.1 ?M. | ||
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产品信息
| 目录号 | A19705 |
|---|---|
| 分子式 | C20H16N2O |
| 分子量 | 300.35 |
| CAS号 | 2143475-98-1 |
| SMILES | CC(NC1=CC=CC=C1C2=CC=CC3=C2NC4=C3C=CC=C4)=O |
| 其他名称 | GeA69; GeA 69 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 52 mg/mL (173.13 mM) | |
| Water | Insoluble | ||
| Ethanol | 9 mg/mL (29.96 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.29 mL | 166.47 mL | 332.94 mL |
| 0.5 mM | 6.66 mL | 33.29 mL | 66.59 mL |
| 1 mM | 3.33 mL | 16.65 mL | 33.29 mL |
| 5 mM | 0.67 mL | 3.33 mL | 6.66 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 2143475-98-1 | 2143475-98-1 供应商 | 2143475-98-1 花费 | 2143475-98-1 生产商 | 订购 2143475-98-1 | 2143475-98-1 代理商