NU 1025
目录号: A15375
PARP 抑制剂
NU 1025 是一种强效的多聚(ADP-核糖)聚合酶（PARP）抑制剂，它能增强一系列机制不同的抗癌药物在 L1210 细胞中的细胞毒性。
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生物活性
| Discription | NU 1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. | ||
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产品信息
| 目录号 | A15375 |
|---|---|
| 分子式 | C9H8N2O2 |
| 分子量 | 176.2 |
| CAS号 | 90417-38-2 |
| SMILES | CC1=NC(=O)C2=C(N1)C(=CC=C2)O |
| 其他名称 | NU1025, NU-1025 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 34 mg/mL (192.99 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 6 mg/mL | ||
| In vivo | 40% PEG 400+saline | 17 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 56.75 mL | 283.77 mL | 567.54 mL |
| 0.5 mM | 11.35 mL | 56.75 mL | 113.51 mL |
| 1 mM | 5.68 mL | 28.38 mL | 56.75 mL |
| 5 mM | 1.14 mL | 5.68 mL | 11.35 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 90417-38-2 | 90417-38-2 供应商 | 90417-38-2 花费 | 90417-38-2 生产商 | 订购 90417-38-2 | 90417-38-2 代理商