|PARP2 (Cell-free assay)||PARP1 (Cell-free assay)||Tankyrase-1 (Cell-free assay)|
|1 nM||5 nM||1.5 μM|
|In vitro (25°C)||DMSO||86 mg/mL (197.94 mM)|
|Water||0.002 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||15% Captisol||15 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||23.01 mL||115.07 mL||230.15 mL|
|0.5 mM||4.6 mL||23.01 mL||46.03 mL|
|1 mM||2.3 mL||11.51 mL||23.01 mL|
|5 mM||0.46 mL||2.3 mL||4.6 mL|
*The above data is based on the productmolecular weight 434.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
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