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INO-1001

PARP 抑制剂

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产品目录号: A10475

库存状态:中国现货中国现货

产品名 目录号 价格 数量
INO-1001 50mg A10475-50
¥ 500.00
INO-1001 100mg A10475-100
¥ 800.00
INO-1001 10mM * 1mL in DMSO A10475-10mM-D
¥ 550.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

INO-1001 is a novel PARP inhibitor, known to sensitize cells to radiation in vitro by inhibiting the repair of DNA damage.

INO-1001

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 INO-1001 发表的文献 (1)
  • Kamada Y, .et al. Castalagin and vescalagin purified from leaves of Syzygium samarangense (Blume) Merrill & L.M. Perry: Dual inhibitory activity against PARP1 and DNA topoisomerase II, Fitoterapia, 2018, Sep;129:94-101 PMID: 29928967

Chemical Information

目录号 A10475
Mechanism of action Inhibitor
分子量 136.2
化学分子式 C7H8N2O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 3544-24-9
Synonyms INO1001
SMILES code C1=CC(=CC(=C1)N)C(=O)N
化学名称 3-Aminobenzamide

生物活性

Description
INO-1001 is a novel PARP inhibitor, known to sensitize cells to radiation in vitro by inhibiting the repair of DNA damage.
Targets
PARP
<50 nM

溶解性

Solubility (25°C) * In vitro DMSO 27 mg/mL (198.31 mM)
Water <1 mg/mL (<1 mM)
Ethanol 27 mg/mL (198.31 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 73.42 mL 367.11 mL 734.21mL
0.5 mM 14.68 mL 73.42 mL 146.84 mL
1 mM 7.34 mL 36.71 mL 73.42 mL
5 mM 1.47 mL 7.34 mL 14.68 mL

*The above data is based on the productmolecular weight 136.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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