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Rucaparib是纯化的全长人PARP-1的有效抑制剂，对LoVo和SW620细胞中的细胞PARP具有更高的抑制作用。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.92 mL | 154.61 mL | 309.21 mL |
| 0.5 mM | 6.18 mL | 30.92 mL | 61.84 mL |
| 1 mM | 3.09 mL | 15.46 mL | 30.92 mL |
| 5 mM | 0.62 mL | 3.09 mL | 6.18 mL |
*The above data is based on the productmolecular weight 323.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14182 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 323.4 |
| Formula | C19H18FN3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 283173-50-2 |
| Synonyms | AG-014699,PF-01367338, AG 014699,PF 01367338, AG014699,PF01367338 |
| SMILES | CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F |
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