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PARP-1 抑制剂

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产品目录号: A14182


产品名 目录号 价格 数量
Rucaparib 5mg A14182-5
¥ 600.00
Rucaparib 10mg A14182-10
¥ 1,000.00
Rucaparib 25mg A14182-25
¥ 2,000.00



Rucaparib is a potent inhibitor of purified full-length human PARP-1 and shows higher inhibition of cellular PARP in LoVo and SW620 cells.





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Chemical Information

目录号 A14182
Mechanism of action Inhibitor
分子量 323.4
化学分子式 C19H18FN3O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 283173-50-2
Synonyms AG-014699,PF-01367338, AG 014699,PF 01367338, AG014699,PF01367338
SMILES code CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F
化学名称 8-?fluoro-?1,?3,?4,?5-?tetrahydro-?2-?[4-?[(methylamino)methyl]phenyl]-?6H-?pyrrolo[4,?3,?2-?ef][2]benzazepin-?6-?one


Rucaparib is a potent inhibitor of purified full-length human PARP-1 and shows higher inhibition of cellular PARP in LoVo and SW620 cells.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.92 mL 154.61 mL 309.21mL
0.5 mM 6.18 mL 30.92 mL 61.84 mL
1 mM 3.09 mL 15.46 mL 30.92 mL
5 mM 0.62 mL 3.09 mL 6.18 mL

*The above data is based on the productmolecular weight 323.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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