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UPF 1069

促销

PARP2 抑制剂

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产品目录号: A12750

库存状态:中国现货中国现货

产品名 目录号 价格 数量
UPF 1069 10mg A12750-10
¥ 800.00
UPF 1069 25mg A12750-25
¥ 1,500.00
UPF 1069 50mg A12750-50
¥ 2,500.00
UPF 1069 100mg A12750-100
¥ 4,000.00
UPF 1069 10mM * 1mL in DMSO A12750-10mM-D
¥ 810.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

UPF 1069 is a selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively).

UPF 1069

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Chemical Information

目录号 A12750
Mechanism of action Inhibitor
分子量 279.29
化学分子式 C17H13NO3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1048371-03-4
Synonyms UPF1069, UPF-1069
SMILES code C1=CC=C(C=C1)C(=O)COC2=CC=CC3=C2C=CNC3=O
化学名称 5-(2-Oxo-2-phenylethoxy)-3,4-dihydr?oisoquinolin-1(2H)-one

生物活性

Description
UPF 1069 is a selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively).
Targets
PARP2 PARP1
0.3 μM8.0 μM

溶解性

Solubility (25°C)* In vitro DMSO 56 mg/mL (200.5 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.81 mL 179.03 mL 358.05mL
0.5 mM 7.16 mL 35.81 mL 71.61 mL
1 mM 3.58 mL 17.9 mL 35.81 mL
5 mM 0.72 mL 3.58 mL 7.16 mL

*The above data is based on the productmolecular weight 279.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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