UPF 1069

目录号: A12750

PARP2 inhibitor

UPF 1069

UPF 1069 Chemical Structure

CAS NO. 1048371-03-4

UPF 1069 is a selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively).

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
25 mg
¥ 1,500.00
50 mg
¥ 2,500.00
100 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 810.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

生物活性

UPF 1069 is a selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively).
Targets
PARP2 PARP1
0.3 μM8.0 μM
In vitro DMSO 56 mg/mL (200.5 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.81 mL 179.03 mL 358.05 mL
0.5 mM 7.16 mL 35.81 mL 71.61 mL
1 mM 3.58 mL 17.9 mL 35.81 mL
5 mM 0.72 mL 3.58 mL 7.16 mL

*The above data is based on the productmolecular weight 279.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

产品技术资料

目录号 A12750
MECHANISM OF ACTION Inhibitor
M. Wt 279.29
Formula C17H13NO3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1048371-03-4
Synonyms UPF1069, UPF-1069
SMILES C1=CC=C(C=C1)C(=O)COC2=CC=CC3=C2C=CNC3=O

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