UPF 1069

目录号: A12750

PARP2 抑制剂

UPF 1069

UPF 1069 Chemical Structure

CAS NO. 1048371-03-4

UPF 1069是一种选择性聚(ADP-核糖)聚合酶(PARP)2抑制剂(PARP-2和PARP-1的IC50值分别为0.3和8.0μM)。

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
25 mg
¥ 1,500.00
50 mg
¥ 2,500.00
100 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 810.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

UPF 1069是一种选择性聚(ADP-核糖)聚合酶(PARP)2抑制剂(PARP-2和PARP-1的IC50值分别为0.3和8.0μM)。
靶点信息
PARP2 PARP1
0.3 μM8.0 μM
In vitro (25°C) DMSO 54 mg/mL (193.34 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.81 mL 179.03 mL 358.05 mL
0.5 mM 7.16 mL 35.81 mL 71.61 mL
1 mM 3.58 mL 17.9 mL 35.81 mL
5 mM 0.72 mL 3.58 mL 7.16 mL

*The above data is based on the productmolecular weight 279.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12750
作用机制 Inhibitor (抑制剂)
M. Wt 279.29
Formula C17H13NO3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1048371-03-4
Synonyms UPF1069, UPF-1069
SMILES C1=CC=C(C=C1)C(=O)COC2=CC=CC3=C2C=CNC3=O

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