UPF 1069
目录号: A12750
PARP2 抑制剂
UPF 1069 是一种选择性的聚(ADP-核糖)聚合酶（PARP）2抑制剂（PARP-2 和 PARP-1 的 IC50 值分别为 0.3 和 8.0 μM）。
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生物活性
| Discription | UPF 1069 is a selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively). | ||
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产品信息
| 目录号 | A12750 |
|---|---|
| 分子式 | C17H13NO3 |
| 分子量 | 279.29 |
| CAS号 | 1048371-03-4 |
| SMILES | C1=CC=C(C=C1)C(=O)COC2=CC=CC3=C2C=CNC3=O |
| 其他名称 | UPF1069, UPF-1069 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 54 mg/mL (193.34 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.81 mL | 179.03 mL | 358.05 mL |
| 0.5 mM | 7.16 mL | 35.81 mL | 71.61 mL |
| 1 mM | 3.58 mL | 17.9 mL | 35.81 mL |
| 5 mM | 0.72 mL | 3.58 mL | 7.16 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1048371-03-4 | 1048371-03-4 供应商 | 1048371-03-4 花费 | 1048371-03-4 生产商 | 订购 1048371-03-4 | 1048371-03-4 代理商