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Talazoparib tosylate (BMN 673ts) is a novel, potent and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.1 mL | 90.49 mL | 180.98 mL |
| 0.5 mM | 3.62 mL | 18.1 mL | 36.2 mL |
| 1 mM | 1.81 mL | 9.05 mL | 18.1 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
*The above data is based on the productmolecular weight 552.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20238 |
|---|---|
| M. Wt | 552.55 |
| Formula | C26H22F2N6O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1373431-65-2 |
| Synonyms | BMN 673ts, BMN-673ts, BMN673ts |
| SMILES | O=C1NN=C2C3=C1C=C(F)C=C3N[C@H](C4=CC=C(F)C=C4)[C@H]2C5=NC=NN5C.O=S(C6=CC=C(C)C=C6)(O)=O |
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