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XAV 939


PARP 抑制剂

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产品目录号: A10994


产品名 目录号 价格 数量
XAV 939 10mg A10994-10
¥ 600.00
XAV 939 25mg A10994-25
¥ 1,200.00
XAV 939 50mg A10994-50
¥ 1,800.00
XAV 939 100mg A10994-100
¥ 2,800.00
XAV 939 10mM * 1mL in DMSO A10994-10mM-D
¥ 550.00



XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).

XAV 939




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 XAV 939 发表的文献 (2)
  • Shizu Aikawa, .et al. Autotaxin每lysophosphatidic acid每LPA 3 signaling at the embryo坼epithelial boundary controls decidualization pathways, EMBO J, 2017, Jul 14; 36(14): 2146每2160 PMID: 28588064
  • Mika?l M. Martino, .et al. Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration, Nat Commun, 2016, 7: 11051 PMID: 27001940

Chemical Information

目录号 A10994
Mechanism of action Inhibitor
分子量 312.3
化学分子式 C14H11F3N2OS
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 284028-89-3
Synonyms XAV939, XAV-939
化学名称 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one


XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).
TNKS2 (Cell-free assay) TNKS1 (Cell-free assay)
4 nM11 nM


Solubility (25°C) * In vitro DMSO 12 mg/mL (38.42 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.02 mL 160.1 mL 320.2mL
0.5 mM 6.4 mL 32.02 mL 64.04 mL
1 mM 3.2 mL 16.01 mL 32.02 mL
5 mM 0.64 mL 3.2 mL 6.4 mL

*The above data is based on the productmolecular weight 312.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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