XAV 939

目录号: A10994

PARP inhibitor

XAV 939

XAV 939 Chemical Structure

CAS NO. 284028-89-3

XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).

库存: 现货

规格 价格 数量
10 mg
¥ 600.00
25 mg
¥ 1,200.00
50 mg
¥ 1,800.00
100 mg
¥ 2,800.00
10mM * 1mL in DMSO
¥ 550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).
Targets
TNKS2 (Cell-free assay) TNKS1 (Cell-free assay)
4 nM11 nM
In vitro (25°C) DMSO 12 mg/mL (38.42 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.02 mL 160.1 mL 320.2 mL
0.5 mM 6.4 mL 32.02 mL 64.04 mL
1 mM 3.2 mL 16.01 mL 32.02 mL
5 mM 0.64 mL 3.2 mL 6.4 mL

*The above data is based on the productmolecular weight 312.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10994
MECHANISM OF ACTION Inhibitor
M. Wt 312.3
Formula C14H11F3N2OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 284028-89-3
Synonyms XAV939, XAV-939
SMILES C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F

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