XAV 939

Name: XAV 939
SKU: A10994

目录号: A10994

PARP 抑制剂

Product Citations (2)

XAV 939 Chemical Structure

CAS NO. 284028-89-3

XAV 939是TNKS抑制剂（TNKS1和TNKS2的IC50值分别为0.011和0.004μM）。

库存：现货

规格	价格	数量
10 mg	￥ 600.00
25 mg	￥ 1,200.00
50 mg	￥ 1,800.00
100 mg	￥ 2,800.00
10mM * 1mL in DMSO	￥ 550.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

XAV 939是TNKS抑制剂（TNKS1和TNKS2的IC50值分别为0.011和0.004μM）。

靶点信息

TNKS2 (Cell-free assay)	TNKS1 (Cell-free assay)
4 nM	11 nM

溶解度 *

In vitro (25°C)	DMSO	12 mg/mL (38.42 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+corn oil	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.02 mL	160.1 mL	320.2 mL
0.5 mM	6.4 mL	32.02 mL	64.04 mL
1 mM	3.2 mL	16.01 mL	32.02 mL
5 mM	0.64 mL	3.2 mL	6.4 mL

*The above data is based on the productmolecular weight 312.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10994
作用机制	Inhibitor (抑制剂)
M. Wt	312.3
Formula	C14H11F3N2OS
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	284028-89-3
Synonyms	XAV939, XAV-939
SMILES	C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F