微信关注
Total item
Cart Subtotal
￥ 0.00 DNA Damage
-
NU-7441 (KU-57788)
Catalog No. A11098 DNA-PK 抑制剂NU-7441 (KU-57788)是一种有效的选择性DNA依赖性蛋白激酶（DNA-PK）抑制剂。对于DNA-PK，mTOR，PI 3-K，ATM和ATR，IC50值分别为14、1700、5000，> 100000和> 100000 nM。 了解更多 -
PIK-75 hydrochloride
Catalog No. A10729 PI3K 抑制剂PIK-75是一种p110α抑制剂，IC50值为5.8nM。在p110γ和p110β的效果较差，IC50值为0.076 ?M和1.3 ?M。 了解更多 -
Compound 401
Catalog No. A11778 DNA-PK 抑制剂Compound 401是一种细胞可渗透的嘧啶-异喹啉酮化合物，可作为有效的，可逆的和ATP竞争的DNA-PK抑制剂（IC50 = 280 nM），选择性是mTOR（IC50 = 5.3μM）的19倍。 了解更多 -
KU 0060648
Catalog No. A13224 DNA-PK 抑制剂KU0060648是一种有效且选择性的DNA依赖性蛋白激酶（DNA-PK）抑制剂（IC50 = 8.6 nM）；对DNA-PK的选择性是其他PIKK的20-1000倍，并且有60种激酶。KU-0060648可提高HDR效率并衰减NHEJ频率。 了解更多 -
ETP-46464
Catalog No. A13328 -
CC-115
Catalog No. A15779 -
NU6027
Catalog No. A14136 -
Nedisertib
Catalog No. A17055 DNA-PK 抑制剂Nedisertib (M-3814,MSC2490484A)是一种可口服的DNA依赖性蛋白激酶（DNA-PK）抑制剂，具有潜在的抗肿瘤和化学/放射增敏活性。 了解更多 -
(Rac)-Nedisertib
Catalog No. A21383 DNA-PK inhibitor(Rac)-Nedisertib ((Rac)-M3814) is a racemate of Nedisertib, a potent DNA-PK inhibitor, with an IC50 of <3 nM. 了解更多 -
Etoposide (VP-16)
Catalog No. A10373 Topoisomerase II 抑制剂Etoposide (VP-16)是通过抑制topoisomerase II活性而抑制DNA合成。 了解更多 -
(-)-Epigallocatechin gallate
Catalog No. A10005 Antioxidant, antiangiogenic, antitumor agent(-)-Epigallocatechin gallate是一种从绿茶中分离出来的强效抗氧化剂多酚类黄酮。 了解更多 -
Genistin (Genistoside)
Catalog No. A10426 Genistin (Genistoside)是一种异黄酮，存在于许多饮食植物中，如大豆和葛根。显示出刺激体内雌激素依赖性乳腺癌细胞生长。 了解更多 -
ABT 492 meglumine (Delafloxacin meglumine)
Catalog No. A15064 ABT 492 meglumine (Delafloxacin meglumine)对喹诺酮敏感和耐药的革兰氏阳性生物更有力，对环丙沙星家族肠杆菌科的某些成员具有类似于环丙沙星的活性，对喹诺酮敏感，非发酵性，革兰氏阴性生物具有类似的活性。 了解更多 -
Idarubicin HCl
Catalog No. A10465 Topoisomerase 抑制剂Idarubicin HCl是蒽环类抗生素，是一种比柔红霉素具有更高DNA结合能力和更大细胞毒性的抗白血病药物。 了解更多 -
Irinotecan
Catalog No. A10478 -
Amonafide (AS1413)
Catalog No. A10071 Topoisomerase 抑制剂Amonafide (AS1413)是一种DNA插入剂和拓扑异构酶II抑制剂，是治疗肿瘤疾病的抗肿瘤药物之一。 了解更多 -
Epirubicin
Catalog No. A12409 Topoisomerase 抑制剂Epirubicin是一种细胞可渗透的抗肿瘤抗生素。阿霉素的立体异构体，其心脏毒性降低。表柔比星的抗肿瘤作用是通过靶向和抑制Topo II（拓扑异构酶II）来介导的。 了解更多 -
Beta-Lapachone
Catalog No. A13059 DNA topoisomerase II 抑制剂Beta-Lapachone是一种选择性的DNA拓扑异构酶I抑制剂，对DNA拓扑异构酶II或连接酶没有抑制活性。 了解更多 -
GENZ-644282
Catalog No. A13206 -
CL2A-SN-38
Catalog No. A18392 DNA Topoisomerase I inhibitorCL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. 了解更多 -
MAC glucuronide phenol-linked SN-38
Catalog No. A18403 DNA topoisomerase I inhibitorMAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively. 了解更多 -
9-amino-CPT
Catalog No. A12540 Topoisomerase I inhibitor9-Aminocamptothecin is a topoisomerase I inhibitor with potent anticancer activity. 了解更多 -
Amsacrine hydrochloride
Catalog No. A17707 antineoplastic agentAmsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. 了解更多 -
Pirarubicin Hydrochloride
Catalog No. A18037 topoisomerase II inhibitorPirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors. 了解更多 -
Gepotidacin
Catalog No. A21086 topoisomerase II inhibitorGepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. 了解更多 -
Karenitecin
Catalog No. A21156 topoisomerase I inhibitorKarenitecin (Cositecan) is a topoisomerase I inhibitor, with potent anti-cancer activity. 了解更多 -
Edotecarin
Catalog No. A21233 Topoisomerase I inhibitorEdotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM. 了解更多 -
Exatecan Mesylate
Catalog No. A21515 DNA topoisomerase I inhibitorExatecan Mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. 了解更多 -
Daunorubicin
Catalog No. A21903 topoisomerase II inhibitorDaunorubicin (Daunomycin; RP 13057; Rubidomycin) is a topoisomerase II inhibitor with potent antineoplastic activities. 了解更多 -
Norfloxacin (Norxacin)
Catalog No. A10652 -
Marbofloxacin
Catalog No. A10557 -
Topotecan HCl (Hycamtin)
Catalog No. A10939 -
Irinotecan HCl Trihydrate (Campto)
Catalog No. A10479 Topoisomerase 抑制剂Irinotecan (CPT 11)是喜树碱家族的一种化合物，是参与细胞DNA复制和转录的拓扑异构酶1的抑制剂。 了解更多 -
ABT-492 (Delafloxacin)
Catalog No. A10023 Fluoroquinolone antibioticABT-492 (Delafloxacin)是一种新的氟喹诺酮类药物，可抵抗155种需氧和171种厌氧菌。 了解更多 -
Adriamycin
Catalog No. A10041 topoisomerase II 抑制剂Adriamycin是一种蒽环类抗生素，它通过插入DNA起作用，而最严重的副作用是危及生命的心脏损害。它通常用于治疗多种癌症，包括血液系统恶性肿瘤，多种类型的癌症和软组织肉瘤。 了解更多
FILTER BY:
购物选项
- 分类
-
- HDAC (102)
- PARP (49)
- DNA-PK (14)
- Topoisomerase (75)
- Telomerase (6)
- ATM / ATR (21)
- DNA, RNA Synthesis (54)
- RNA/DNA Polymerase (21)
- DNA alkylator (8)
- Synthases / Synthetases (17)
- MTH1 (3)
- Sirtuins (30)
- IRE1 (2)
- DNA Stain (19)
- 作用机制
-
- Inhibitor (抑制剂) (305)
- Agonist (激动剂) (1)
- Activator (激活剂) (11)
- Degrader (降解剂) (1)
- Substrate (底物) (2)
- 靶点
-
- DNA-PK (1)
- DNMT (1)
- EGFR (1)
- HD1 (2)
- HD2 (1)
- HDAC (21)
- HDAC1 (24)
- HDAC10 (4)
- HDAC11 (4)
- HDAC2 (15)
- HDAC3 (19)
- HDAC4 (6)
- HDAC5 (4)
- HDAC6 (23)
- HDAC7 (2)
- HDAC8 (9)
- HDAC9 (3)
- HER2 (1)
- Mdm2 (1)
- MdmX (1)
- NF-κB (1)
- p110α (2)
- p110β (2)
- p110γ (2)
- p110δ (2)
- p53 (2)
- PARP (13)
- PARP1 (10)
- PARP2 (4)
- PDE5 (1)
- SIRT1 (6)
- SIRT2 (5)
- SIRT3 (1)
- Sirtuin (1)
- Tankyrase-1 (5)
- Tankyrase-2 (8)
ADOOQ 产品质量保证
We promise all products to perform as described.