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￥ 0.00 PI3K / Akt / mTOR
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PI4KIII beta inhibitor 3
Catalog No. A15430 -
VPS34-IN1
Catalog No. A15874 -
MLN1117 (Serabelisib)
Catalog No. A15529 p110α 抑制剂MLN1117，也称为INK1117和TAK-117，是具有潜在抗肿瘤活性的I类磷酸肌醇3激酶（PI3K）α同工型的生物利用抑制剂。 了解更多 -
Desmethyl-VS-5584
Catalog No. A10900 -
Tenalisib (RP6530)
Catalog No. A16799 dual PI3Kδ/γ 抑制剂Tenalisib (RP6530)是一种有效且选择性的双重PI3Kδ/PI3Kγ抑制剂，能抑制B细胞淋巴瘤细胞系的生长，同时降低下游生物标记物pAKT。 了解更多 -
Seletalisib (UCB-5857)
Catalog No. A16797 PI3K 抑制剂Seletalisib (UCB-5857)是一种新型的PI3Kδ小分子抑制剂，其IC50值为12 nM，相对于其他I类PI3K亚型（介于24-303倍之间），对PI3Kδ具有显著的选择性。 了解更多 -
leniolisib (CDZ 173)
Catalog No. A16796 PI3K 抑制剂Leniolisib (CDZ 173)是一种有效的、选择性的PI3Kδ抑制剂，对PI3Kα、PI3Kβ、PI3Kγ和PI3Kδ的生化IC50值分别为0.244、0.424、2.23和0.011 uM。 了解更多 -
Vps34-IN-2
Catalog No. A16933 Vps34 抑制剂Vps34-IN-2是一种新颖，有效和选择性的Vps34抑制剂，在Vps34酶促测定和GFP-FYVE细胞测定中的IC50分别为2和82 nM。 了解更多 -
SAR260301
Catalog No. A16877 -
Pictilisib dimethanesulfonate
Catalog No. A11444 PI3Kα/δ inhibitorPictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). 了解更多 -
Dactolisib Tosylate
Catalog No. A11327 dual PI3K and mTOR kinase inhibitorDactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2. 了解更多 -
Parsaclisib
Catalog No. A13561 PI3Kδ inhibitorParsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases. 了解更多 -
CAL-130 Racemate
Catalog No. A20942 PI3Kδ inhibitorCAL-130 Racemate is the racemate of CAL-130. CAL-130 Racemate is a PI3Kδ inhibitor. 了解更多 -
Alpelisib hydrochloride
Catalog No. A21794 PI3Kα inhibitorAlpelisib hydrochloride (BYL-719 hydrochloride) is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, p110δ, and p110β, respectively. 了解更多 -
Umbralisib R-enantiomer
Catalog No. A21993 PI3Kδ inhibitorUmbralisib R-enantiomer (TGR-1202 R-enantiomer) is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202. 了解更多 -
GSK2292767
Catalog No. A16564 PI3Kδ inhibitorGSK2292767 is a potent and selective inhibitor of phosphatidylinositol 3-kinase δ (PI3Kδ; Ki = 79 pM). GSK2292767 is >100-fold selective for PI3Kδ over a panel of 250 kinases. 了解更多 -
PI3Kdelta inhibitor 1
Catalog No. A19249 PI3Kδ inhibitorPI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3Kδ inhibitor with an IC50 of 1.3 nM. 了解更多 -
CHMFL-PI3KD-317
Catalog No. A19990 PI3Kδ inhibitorCHMFL-PI3KD-317 is a highly potent, selective and orally active PI3Kδ inhibitor, with an IC50 of 6 nM. 了解更多 -
VS-5584
Catalog No. A12480 -
Panulisib (P7170, AK151761)
Catalog No. A14379 -
AZD8186
Catalog No. A14164 -
CAL-130
Catalog No. A15030 -
CAL-130 Hydrochloride
Catalog No. A15031 PI3K 抑制剂CAL-130 Hydrochloride是一种新型的磷酸肌醇3激酶（PI3K）抑制剂。据报道，PI3Kδ/γ的联合抑制可作为T细胞急性淋巴细胞白血病（T-ALL）的疗法。 了解更多 -
LY 303511
Catalog No. A15147 -
NVP-BKM120 Hydrochloride
Catalog No. A15195 PI3K 抑制剂?NVP-BKM120 Hydrochloride是p110α/β/δ/γ的选择性PI3K抑制剂，IC50分别为52 nM/166 nM/116 nM/262 nM。对VPS34，mTOR，DNA-PK的效力降低，对PI4Kβ几乎没有活性。 了解更多 -
PI-103 Hydrochloride
Catalog No. A15212 PI3K 抑制剂PI-103 Hydrochloride是对重组PI3K亚型p110alpha（IC50 = 2 nM），p110beta（IC50 = 3 nM），p110delta（IC50 = 3 nM）和p110gamma（IC50 = 15 nM）具有低IC50值的有效抑制剂，对mTOR的效力较低/DNA-PK，IC50为30 nM/23 nM。 了解更多 -
XL-147 (Pilaralisib)
Catalog No. A15283 -
Acalisib (GS-9820)
Catalog No. A14441 PI3Kδ 抑制剂Acalisib (GS-9820)是IA类磷酸肌醇3激酶（PI3K）的110 kDa催化亚基的β和δ异构体的抑制剂，具有潜在的免疫调节和抗肿瘤活性。 了解更多 -
AMG319
Catalog No. A15901 -
PF-4989216
Catalog No. A12889 PI3K 抑制剂PF-4989216是一种有效的选择性PI3K抑制剂，对p110α，p110β，p110γ，p110δ和VPS34的IC50分别为2 nM，142 nM，65 nM，1 nM和110 nM。 了解更多 -
PQR309 (Bimiralisib)
Catalog No. A15992 -
GNE-317
Catalog No. A13992 -
PI4KIIIbeta-IN-10
Catalog No. A16269 PI4KIIIβ 抑制剂PI4KIIIbeta-IN-10是目前报道的最有效的PI4KIIIbeta抑制剂，对PI4KIIIbeta相关的脂质激酶的脱靶抑制作用很小（IC50 = 3.6 nM）。 了解更多 -
PI4KIIIbeta-IN-9
Catalog No. A16270 PI4KIIIβ 抑制剂PI4KIIIbeta-IN-9是一种有效的PI4KIIIbeta抑制剂（IC50为7 nM），选择性是PI3Kgamma的140倍以上，选择性是PI3Kδ的20倍以上，并且在浓度高达20 uM时，对vps34没有抑制作用。 了解更多
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