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Abiraterone (CB-7598)是一种有效CYP17抑制剂，20裂合酶（CYP17A1）。
靶点信息
| CYP17 (Cell-free assay) | ||||
| 2 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.64 mL | 143.18 mL | 286.37 mL |
| 0.5 mM | 5.73 mL | 28.64 mL | 57.27 mL |
| 1 mM | 2.86 mL | 14.32 mL | 28.64 mL |
| 5 mM | 0.57 mL | 2.86 mL | 5.73 mL |
*The above data is based on the productmolecular weight 349.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10020 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 349.2 |
| Formula | C24H31NO |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 154229-19-3 |
| Synonyms | CB-7598, CB7598 |
| SMILES | C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CN=CC=C5)C)O |
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