nAChR

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  1. (-)-(S)-B-973B

    Catalog No. A18761
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    α7 nAChR modulator
    -)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activity. 了解更多
  2. Mecamylamine Hydrochloride

    Catalog No. A17884
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    nAChR antagonist
    Mecamylamine hydrochloride is a nAChR antagonist previously used to treat hypertension. It displays a wide variety of activities, including reducing depression-like behaviors in subjects with Tourette's syndrome and improving rates of smoking cessation. 了解更多
  3. Benzethonium Chloride

    Catalog No. A13653
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    nAChR 抑制剂
    Benzethonium Chloride是nAChRs的有效抑制剂,可抑制α4β2nAChRs和α7nAChRs,IC50分别为49 nM和122 nM。 了解更多
  4. GTS-21 (DMBX-A)

    Catalog No. A15950
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    nAChR 激动剂
    GTS-21 dihydrochloride (DMBX-A)是一种选择性的α7烟碱乙酰胆碱受体激动剂,最近已被确定为一种有希望的炎症治疗方法。 了解更多
  5. EVP-6124 hydrochloride

    Catalog No. A15087
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    nAChR 抑制剂
    EVP-6124 hydrochloride是一种新型的α7神经元烟碱型乙酰胆碱受体(nAChRs)的部分激动剂。EVP-6124对α7nAChRs具有选择性,并且不激活或抑制异源α4β2nAChRs。 了解更多
  6. EVP-6124 (Encenicline)

    Catalog No. A15086
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    nAChR 抑制剂
    EVP-6124 (Encenicline)是α7神经元烟碱乙酰胆碱受体(nAChRs)的新型部分激动剂;显示对α7nAChRs的选择性,并且不激活或抑制异聚体α4β2nAChRs。 了解更多
  7. A-582941

    Catalog No. A13539
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    α7 nAChR 激动剂
    A-582941是选择性的AChR a7部分激动剂。它对大鼠和人类a7受体均表现出高亲和力(Ki值分别为10.8和16.7 nM)。 了解更多
  8. 5-Iodo-A-85380 2HCl

    Catalog No. A13639
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    nAChR 激动剂
    5-Iodo-A-85380 2HCl是针对a4b2和a6b2烟碱乙酰胆碱受体的强效亚型选择性激动剂。 了解更多
  9. ABT-418 HCl

    Catalog No. A13688
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    nAChR 激动剂
    ABT-418 HCl是神经元烟碱型乙酰胆碱受体激动剂。 了解更多
  10. Sofinicline (ABT-894, A-422894)

    Catalog No. A13842
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    nAChR 激动剂
    Sofinicline (ABT-894,A-422894)是一种新型的烟碱型乙酰胆碱受体激动剂,可治疗注意力不足/多动症。 了解更多
  11. Ispronicline (TC-1734, AZD-3480)

    Catalog No. A14183
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    nAChR 激动剂
    Ispronicline (TC-1734,AZD-3480)是神经元烟碱乙酰胆碱受体部分激动剂。Ispronicline是亚型选择性的,主要与a4b2亚型结合。它具有抗抑郁、益智和神经保护作用。 了解更多
  12. A-867744

    Catalog No. A11290
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    modulator of α7 nAChRs
    A-867744是α7烟碱乙酰胆碱受体的新型正变构调节剂。 了解更多
  13. PNU 282987

    Catalog No. A11233
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    α7 nAChR 激动剂
    PNU 282987 (PNU-282,987)可作为神经烟碱乙酰胆碱受体α7亚型的有效选择性激动剂。 了解更多
  14. Bephenium hydroxynaphthoate

    Catalog No. A17391
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    B-type AChR activator
    Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator. 了解更多
  15. CCMI

    Catalog No. A21534
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    α7 nAChR-positive allosteric modulator
    CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. 了解更多
  16. Varenicline Hydrochloride

    Catalog No. A21539
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    α4β2 nAChR partial agonist
    Varenicline Hydrochloride (CP 526555 hydrochloride) is a high affinity, selective α4β2 nicotine acetylcholine receptor (nAChR) partial agonist and full α7 nAChR agonist. 了解更多
  17. Tebanicline hydrochloride

    Catalog No. A21918
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    nAChR modulator
    Tebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. 了解更多
  18. Bephenium

    Catalog No. A21680
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    AChR activator
    Bephenium is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator. 了解更多
  19. BNC375

    Catalog No. A18503
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    α7 nAChR Modulator
    BNC375 is a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs. 了解更多
  20. Tropisetron HCL

    Catalog No. A14375
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    5-HT3 receptor 拮抗剂
    Tropisetron HCL是选择性的5-HT3受体拮抗剂和α7烟碱样受体激动剂,对5-HT3受体的IC50为70.1±0.9 nM。 了解更多
  21. Methyllycaconitine citrate

    Catalog No. A12681
    Methyllycaconitine citrate是含有α7的神经元烟碱受体(Ki = 1.4 nM)的有效拮抗剂。与浓度大于40 nM的α4β2和α6β2受体相互作用。 了解更多
  22. Adiphenine HCl

    Catalog No. A11716
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    AChR抑制剂
    Adiphenine Hydrochloride是烟碱受体抑制剂,IC50为15μM,用作解痉药物。 了解更多
  23. Varenicline

    Catalog No. A10966
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    nAChR partial agonist
    Varenicline是烟碱样受体部分激动剂。 了解更多
  24. PNU-120596

    Catalog No. A11203
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    Nicotinic (α7) Receptor Modulator
    PNU-120596是α7神经元烟碱型乙酰胆碱受体的正变构调节剂。 了解更多

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