Histone Acetyltransferases

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  1. Histone Acetyltransferase Inhibitor II

    Catalog No. A12331
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    cell permeable p300 inhibitor
    Histone Acetyltransferase Inhibitor II is a potent and cell permeable p300 inhibitor, with an IC50 of 5 ?M; Histone Acetyltransferase Inhibitor II can be used in cancer research. 了解更多
  2. SGC-CBP30

    Catalog No. A13227
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    CBP/p300 bromodomain 抑制剂
    SGC-CBP30是一种有效且选择性的CREBBP(CBP)和EP300抑制剂,无细胞试验中IC50分别为21 nM和38 nM。它们是一般的转录共激活因子。 了解更多
  3. I-CBP112

    Catalog No. A13165
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    CBP/p300 bromodomain 抑制剂
    I-CBP112是一种高效且选择性的p300/CBP溴结构域抑制剂(对于CBP,IC50为?0.14-0.17 uM,对于p300为?0.625 uM)。 了解更多
  4. TPOP146

    Catalog No. A12655
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    CBP/P300 benzoxazepine bromodomain inhibitor
    TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4. 了解更多
  5. GNE-049

    Catalog No. A20206
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    CBP inhibitor
    GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively. 了解更多
  6. PRI-724

    Catalog No. A15856
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    CBP/beta-catenin 拮抗剂
    PRI-724是ICG-001的异构体或对映异构体,是一种强力的特异性抑制剂癌症干细胞中的Wnt信号通路具有潜在的抗肿瘤活性。 了解更多
  7. EML 425

    Catalog No. A16180
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    CBP/p300 抑制剂
    EML 425是一种可逆且非竞争性的CBP/p300抑制剂,具有细胞渗透性(IC50值分别为1.1和2.9 uM)。 了解更多
  8. CPI-637

    Catalog No. A16470
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    CBP/EP300 bromodomain 抑制剂
    CPI-637是一种选择性的,具有细胞活性的苯并二氮杂酮CBP/EP300溴结构域抑制剂。 了解更多
  9. CTPB

    Catalog No. A18558
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    p300 HAT activator
    CTPB is an activator of p300 HAT (histone acetyltransferase) without PCAF (p300/CBP-associated factor) HAT activities. 了解更多
  10. A-485

    Catalog No. A16830
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    p300/CBP 抑制剂
    A-485是p300/CBP的强效选择性HAT抑制剂,在p300 TR-FRET分析中的IC50为10 nM,在CBP TR-FRET分析中的IC50为3 nM,选择性是紧密相关的HAT的1000倍以上。 了解更多
  11. E-7386

    Catalog No. A17089
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    CBP/beta-catenin modulator
    E-7386是一种活性CBP /β-catenin调节剂。 了解更多
  12. GNE-207

    Catalog No. A18844
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    CBP bromodomain inhibitor
    GNE-207 is a novel, potent, and orally bioavailable inhibitor of the bromodomain of CBP. GNE-207 has excellent CBP potency (CBP IC50?=?1?nM, MYC EC50?=?18?nM), and it exhibits a good pharmacokinetic profile. 了解更多
  13. YF-2

    Catalog No. A21018
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    histone acetyltransferase activator
    YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease. 了解更多
  14. Remodelin

    Catalog No. A21985
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    acetyl-transferase protein NAT10 inhibitor
    Remodelin is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. 了解更多
  15. P300/CBP-IN-3

    Catalog No. A18544
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    p300/CBP histone acetyltransferase inhibitor
    P300/CBP-IN-3, a p300/CBP histone acetyltransferase inhibitor. 了解更多
  16. WM-1119

    Catalog No. A16828
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    lysine acetyltransferase KAT6A 抑制剂
    WM-1119是赖氨酸乙酰基转移酶KAT6A的高效选择性抑制剂,IC50为0.25 uM。它对KAT6A的活性分别是对KAT5或KAT7的1100倍和250倍。 了解更多
  17. MG149

    Catalog No. A14267
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    KAT5 (Tip60) HAT 抑制剂
    MG149是一种有效的组蛋白乙酰转移酶抑制剂,对Tip60和MOF的IC50为74 uM和47 uM。 了解更多
  18. Remodelin Hydrobromide

    Catalog No. A14215
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    NAT10 抑制剂
    Remodelin Hydrobromide是一种有效的乙酰转移酶NAT10抑制剂。 了解更多
  19. Anacardic Acid

    Catalog No. A14226
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    KAT5 (Tip60), p300/PCAF 抑制剂
    Anacardic Acid是p300和p300/CBP相关因子组蛋白乙酰转移酶的有效抑制剂。 了解更多
  20. NU 9056

    Catalog No. A13378
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    KAT5 (Tip60) HAT 抑制剂
    NU9056是一种选择性KAT5(Tip60)HAT抑制剂。对于KAT5,p300,pCAF和GCN5,IC50值分别为<2、60、36和> 100μM。抑制前列腺癌细胞系和蛋白质块中的蛋白质乙酰化。 了解更多
  21. C646

    Catalog No. A12815
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    p300/CBP 抑制剂
    C646是选择性的p300/CREB结合蛋白(CBP)抑制剂(Ki = 400 nM)。 了解更多
  22. Garcinol

    Catalog No. A12814
    HAT 抑制剂
    藤黄酚是从印度藤黄中分离的聚异戊二烯基二苯甲酮衍生物。 在体外和体内,它都是有效的组蛋白乙酰转移酶(HATs)p300(IC50 = 7?M)和PCAF(IC50 = 5?M)抑制剂。 了解更多

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