Dorzolamide HCL

目录号: A10333

carbonic anhydrase 抑制剂

Dorzolamide HCL

Dorzolamide HCL Chemical Structure

CAS NO. 130693-82-2

Dorzolamide HCl是一种碳酸酐酶抑制剂。它是一种抗青光眼剂,以滴眼剂的形式局部使用。盐酸度尔佐胺用于降低开角型青光眼和高眼压患者的眼内压升高。

库存: 现货

规格 价格 数量
10 mg
¥ 600.00
50 mg
¥ 1,000.00
100 mg
¥ 1,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Dorzolamide HCl是一种碳酸酐酶抑制剂。它是一种抗青光眼剂,以滴眼剂的形式局部使用。盐酸度尔佐胺用于降低开角型青光眼和高眼压患者的眼内压升高。
靶点信息
Carbonic anhydrase II Carbonic anhydrase IV Carbonic anhydrase I
1.9 nM(Ki)31 nM(Ki)6000 nM(Ki)
In vitro DMSO Insoluble
Water 12 mg/mL (33.25 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.71 mL 138.54 mL 277.09 mL
0.5 mM 5.54 mL 27.71 mL 55.42 mL
1 mM 2.77 mL 13.85 mL 27.71 mL
5 mM 0.55 mL 2.77 mL 5.54 mL

*The above data is based on the productmolecular weight 360.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10333
作用机制 Inhibitor (抑制剂)
M. Wt 360.9
Formula C10H17ClN2O4S3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 130693-82-2
Synonyms Trusopt, Cosopt
SMILES CCN[C@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl

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